Linked Life Data

20139923

Source:http://linkedlifedata.com/resource/pubmed/id/20139923

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:20139923rdf:typepubmed:Citationlld:pubmed
pubmed-article:20139923lifeskim:mentionsumls-concept:C1522318lld:lifeskim
pubmed-article:20139923lifeskim:mentionsumls-concept:C0741968lld:lifeskim
pubmed-article:20139923lifeskim:mentionsumls-concept:C1280412lld:lifeskim
pubmed-article:20139923lifeskim:mentionsumls-concept:C0221099lld:lifeskim
pubmed-article:20139923lifeskim:mentionsumls-concept:C0806140lld:lifeskim
pubmed-article:20139923lifeskim:mentionsumls-concept:C0599949lld:lifeskim
pubmed-article:20139923lifeskim:mentionsumls-concept:C1514307lld:lifeskim
pubmed-article:20139923lifeskim:mentionsumls-concept:C2347957lld:lifeskim
pubmed-article:20139923lifeskim:mentionsumls-concept:C1705117lld:lifeskim
pubmed-article:20139923lifeskim:mentionsumls-concept:C0857121lld:lifeskim
pubmed-article:20139923pubmed:issue4lld:pubmed
pubmed-article:20139923pubmed:dateCreated2010-4-6lld:pubmed
pubmed-article:20139923pubmed:abstractTextCoronary microcirculation is disturbed in patients with arterial hypertension. Carotid intima-media thickness (IMT) and arterial stiffness are markers of subclinical atherosclerosis with prognostic significance. We investigated whether the combination of increased carotid IMT and arterial stiffness has a greater predictive value for the presence of impaired coronary flow reserve (CFR) than each index alone in never-treated hypertensives. We studied 110 untreated patients (age: 54.5+/-12 years) with newly diagnosed arterial hypertension. We measured (1) carotid-to-femoral artery pulse wave velocity (PWV), (2) carotid IMT and (3) CFR by means of color-guided Doppler echocardiography after adenosine infusion. Among other confounders, arterial stiffness and IMT were independent determinants of CFR (coefficient B=-0.146 and B=-0.006, P<0.05). Arterial stiffness and IMT had an incremental value for the determination of CFR when added to a model including other confounders (chi(2) change=4.423, P for change=0.038 after addition of IMT; and chi(2) change=5.369, P for change=0.020 after addition of PWV). Receiver operating curve analysis showed that PWV>10.2 m s(-1) and IMT>1 mm were the optimal cutoff values to predict a CFR<2.5. Patients with IMT>1 mm, PWV>10.2 m s(-1) or their combination had an odds ratio of 3.5, 5.0 and 11.2, P<0.05, for a CFR<2.5, respectively. The combination of increased carotid IMT and arterial stiffness has a greater predictive value for impaired CFR than each index alone in never-treated hypertensives.lld:pubmed
pubmed-article:20139923pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:20139923pubmed:languageenglld:pubmed
pubmed-article:20139923pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:20139923pubmed:citationSubsetIMlld:pubmed
pubmed-article:20139923pubmed:statusMEDLINElld:pubmed
pubmed-article:20139923pubmed:monthAprlld:pubmed
pubmed-article:20139923pubmed:issn1348-4214lld:pubmed
pubmed-article:20139923pubmed:authorpubmed-author:KremastinosD...lld:pubmed
pubmed-article:20139923pubmed:authorpubmed-author:ParissisJohnJlld:pubmed
pubmed-article:20139923pubmed:authorpubmed-author:IkonomidisIgn...lld:pubmed
pubmed-article:20139923pubmed:authorpubmed-author:LekakisJohnJlld:pubmed
pubmed-article:20139923pubmed:authorpubmed-author:Paraskevaidis...lld:pubmed
pubmed-article:20139923pubmed:authorpubmed-author:Triantafyllid...lld:pubmed
pubmed-article:20139923pubmed:authorpubmed-author:Anastasiou-Na...lld:pubmed
pubmed-article:20139923pubmed:authorpubmed-author:PapadopoulosC...lld:pubmed
pubmed-article:20139923pubmed:authorpubmed-author:TzortzisStavr...lld:pubmed
pubmed-article:20139923pubmed:authorpubmed-author:TrivilouParas...lld:pubmed
pubmed-article:20139923pubmed:issnTypeElectroniclld:pubmed
pubmed-article:20139923pubmed:volume33lld:pubmed
pubmed-article:20139923pubmed:ownerNLMlld:pubmed
pubmed-article:20139923pubmed:authorsCompleteYlld:pubmed
pubmed-article:20139923pubmed:pagination367-73lld:pubmed
pubmed-article:20139923pubmed:meshHeadingpubmed-meshheading:20139923...lld:pubmed
pubmed-article:20139923pubmed:meshHeadingpubmed-meshheading:20139923...lld:pubmed
pubmed-article:20139923pubmed:meshHeadingpubmed-meshheading:20139923...lld:pubmed
pubmed-article:20139923pubmed:meshHeadingpubmed-meshheading:20139923...lld:pubmed
pubmed-article:20139923pubmed:meshHeadingpubmed-meshheading:20139923...lld:pubmed
pubmed-article:20139923pubmed:meshHeadingpubmed-meshheading:20139923...lld:pubmed
pubmed-article:20139923pubmed:meshHeadingpubmed-meshheading:20139923...lld:pubmed
pubmed-article:20139923pubmed:meshHeadingpubmed-meshheading:20139923...lld:pubmed
pubmed-article:20139923pubmed:meshHeadingpubmed-meshheading:20139923...lld:pubmed
pubmed-article:20139923pubmed:meshHeadingpubmed-meshheading:20139923...lld:pubmed
pubmed-article:20139923pubmed:meshHeadingpubmed-meshheading:20139923...lld:pubmed
pubmed-article:20139923pubmed:meshHeadingpubmed-meshheading:20139923...lld:pubmed
pubmed-article:20139923pubmed:meshHeadingpubmed-meshheading:20139923...lld:pubmed
pubmed-article:20139923pubmed:meshHeadingpubmed-meshheading:20139923...lld:pubmed
pubmed-article:20139923pubmed:year2010lld:pubmed
pubmed-article:20139923pubmed:articleTitleIncremental predictive value of carotid intima-media thickness to arterial stiffness for impaired coronary flow reserve in untreated hypertensives.lld:pubmed
pubmed-article:20139923pubmed:affiliationSecond Cardiology Department, Attikon Hospital, University of Athens, Athens, Greece.lld:pubmed
pubmed-article:20139923pubmed:publicationTypeJournal Articlelld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:20139923lld:pubmed