| pubmed-article:20122575 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20122575 | lifeskim:mentions | umls-concept:C0332256 | lld:lifeskim |
| pubmed-article:20122575 | lifeskim:mentions | umls-concept:C2000611 | lld:lifeskim |
| pubmed-article:20122575 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:20122575 | pubmed:dateCreated | 2010-2-3 | lld:pubmed |
| pubmed-article:20122575 | pubmed:abstractText | Two copper(II) complexes, [Cu(sac)(2)(4-cypy)(2)(H(2)O)], 1 and [Cu(sac)(2)(4-Ampy)(2)(H(2)O)], 2 (4-cypy: 4-cyanopyridine; 4-Ampy: 4-aminopyridine) were prepared. Physicochemical properties of the complexes were studied by spectroscopic (solution UV-vis, diffuse reflectance and IR) techniques. Structural X-ray diffraction data could be obtained only for [Cu(sac)(2)(4-cypy)(2)(H(2)O)] that it crystallized in the tetragonal space group P4cc with a=b=15.313(1), c=13.240(1)A, and Z=4 molecules per unit cell. The complex was cited on a crystallographic C(2)-axis with the Cu(II) ion in a square-pyramidal environment, coordinated at the pyramid basis to the nitrogen atom of two saccharine anions [d(Cu-N)=2.011(3)A] and the pyridine N-atom of two 4-cyanopyridine ligands [d(Cu-N)=2.038(4)A]. The coordination was completed by a water molecule at the pyramid apex [d(Cu-Ow)=2.189(5)A]. Elemental and spectroscopic analyses revealed an O-saccharinate coordination mode for complex 2 and a square-pyramidal structure. Only complex 2 retained its structure in methanolic solution. However, both complexes were able to catalyze the dismutation of superoxide anion (O(2)(-)) (pH 7.5) at micromolar concentrations. Therefore, these complexes behaved as useful SOD-mimetic compounds. | lld:pubmed |
| pubmed-article:20122575 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20122575 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20122575 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:20122575 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20122575 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20122575 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20122575 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20122575 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20122575 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20122575 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20122575 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20122575 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:20122575 | pubmed:issn | 1878-3252 | lld:pubmed |
| pubmed-article:20122575 | pubmed:author | pubmed-author:SupersteinEE | lld:pubmed |
| pubmed-article:20122575 | pubmed:author | pubmed-author:WilliamsPatri... | lld:pubmed |
| pubmed-article:20122575 | pubmed:author | pubmed-author:FerrerEvelina... | lld:pubmed |
| pubmed-article:20122575 | pubmed:author | pubmed-author:PiroOscar EOE | lld:pubmed |
| pubmed-article:20122575 | pubmed:author | pubmed-author:BaezaNataliaN | lld:pubmed |
| pubmed-article:20122575 | pubmed:author | pubmed-author:NasoLuciana... | lld:pubmed |
| pubmed-article:20122575 | pubmed:copyrightInfo | Copyright 2009 Elsevier GmbH. All rights reserved. | lld:pubmed |
| pubmed-article:20122575 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:20122575 | pubmed:volume | 24 | lld:pubmed |
| pubmed-article:20122575 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20122575 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20122575 | pubmed:pagination | 20-6 | lld:pubmed |
| pubmed-article:20122575 | pubmed:meshHeading | pubmed-meshheading:20122575... | lld:pubmed |
| pubmed-article:20122575 | pubmed:meshHeading | pubmed-meshheading:20122575... | lld:pubmed |
| pubmed-article:20122575 | pubmed:meshHeading | pubmed-meshheading:20122575... | lld:pubmed |
| pubmed-article:20122575 | pubmed:meshHeading | pubmed-meshheading:20122575... | lld:pubmed |
| pubmed-article:20122575 | pubmed:meshHeading | pubmed-meshheading:20122575... | lld:pubmed |
| pubmed-article:20122575 | pubmed:meshHeading | pubmed-meshheading:20122575... | lld:pubmed |
| pubmed-article:20122575 | pubmed:meshHeading | pubmed-meshheading:20122575... | lld:pubmed |
| pubmed-article:20122575 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:20122575 | pubmed:articleTitle | Superoxidedismutase-mimetic copper(II) complexes containing saccharinate and 4-aminopyridine/4-cyanopyridine. | lld:pubmed |
| pubmed-article:20122575 | pubmed:affiliation | Centro de Química Inorgánica (CEQUINOR/CONICET, UNLP), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, C. Correo 962, 1900 La Plata, Argentina. | lld:pubmed |
| pubmed-article:20122575 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:20122575 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
