| pubmed-article:20116904 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20116904 | lifeskim:mentions | umls-concept:C0013216 | lld:lifeskim |
| pubmed-article:20116904 | lifeskim:mentions | umls-concept:C0017636 | lld:lifeskim |
| pubmed-article:20116904 | lifeskim:mentions | umls-concept:C0033262 | lld:lifeskim |
| pubmed-article:20116904 | lifeskim:mentions | umls-concept:C0812407 | lld:lifeskim |
| pubmed-article:20116904 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:20116904 | lifeskim:mentions | umls-concept:C0056789 | lld:lifeskim |
| pubmed-article:20116904 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:20116904 | pubmed:dateCreated | 2010-3-8 | lld:pubmed |
| pubmed-article:20116904 | pubmed:abstractText | The first glucuronide prodrug of the hedgehog signaling inhibitor cyclopamine was synthesized. The carbamoyl derivatisation of cyclopamine significantly decreased its toxicity towards the U87 human glioblastoma cell line. However, when the prodrug was incubated with beta-glucuronidase in the culture media, the active drug was efficiently released thereby restoring its anti-proliferative activity. | lld:pubmed |
| pubmed-article:20116904 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20116904 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20116904 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:20116904 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20116904 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20116904 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20116904 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20116904 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20116904 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20116904 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:20116904 | pubmed:issn | 1768-3254 | lld:pubmed |
| pubmed-article:20116904 | pubmed:author | pubmed-author:RenouxBrigitt... | lld:pubmed |
| pubmed-article:20116904 | pubmed:author | pubmed-author:MullerJean-Ma... | lld:pubmed |
| pubmed-article:20116904 | pubmed:author | pubmed-author:ChadéneauCori... | lld:pubmed |
| pubmed-article:20116904 | pubmed:author | pubmed-author:PapotSébastie... | lld:pubmed |
| pubmed-article:20116904 | pubmed:author | pubmed-author:HamonFlorianF | lld:pubmed |
| pubmed-article:20116904 | pubmed:copyrightInfo | Copyright (c) 2010 Elsevier Masson SAS. All rights reserved. | lld:pubmed |
| pubmed-article:20116904 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:20116904 | pubmed:volume | 45 | lld:pubmed |
| pubmed-article:20116904 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20116904 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20116904 | pubmed:pagination | 1678-82 | lld:pubmed |
| pubmed-article:20116904 | pubmed:meshHeading | pubmed-meshheading:20116904... | lld:pubmed |
| pubmed-article:20116904 | pubmed:meshHeading | pubmed-meshheading:20116904... | lld:pubmed |
| pubmed-article:20116904 | pubmed:meshHeading | pubmed-meshheading:20116904... | lld:pubmed |
| pubmed-article:20116904 | pubmed:meshHeading | pubmed-meshheading:20116904... | lld:pubmed |
| pubmed-article:20116904 | pubmed:meshHeading | pubmed-meshheading:20116904... | lld:pubmed |
| pubmed-article:20116904 | pubmed:meshHeading | pubmed-meshheading:20116904... | lld:pubmed |
| pubmed-article:20116904 | pubmed:meshHeading | pubmed-meshheading:20116904... | lld:pubmed |
| pubmed-article:20116904 | pubmed:meshHeading | pubmed-meshheading:20116904... | lld:pubmed |
| pubmed-article:20116904 | pubmed:meshHeading | pubmed-meshheading:20116904... | lld:pubmed |
| pubmed-article:20116904 | pubmed:meshHeading | pubmed-meshheading:20116904... | lld:pubmed |
| pubmed-article:20116904 | pubmed:meshHeading | pubmed-meshheading:20116904... | lld:pubmed |
| pubmed-article:20116904 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:20116904 | pubmed:articleTitle | Study of a cyclopamine glucuronide prodrug for the selective chemotherapy of glioblastoma. | lld:pubmed |
| pubmed-article:20116904 | pubmed:affiliation | Université de Poitiers, UMR-CNRS 6514, 40 avenue du Recteur Pineau, 86022 Poitiers, France. | lld:pubmed |
| pubmed-article:20116904 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:20116904 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:20116904 | lld:chembl |
