TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis through increased aerobic glycolysis and HIF1alpha stabilization.

Source:http://linkedlifedata.com/resource/pubmed/id/20103683

Clin. Cancer Res. 2010 Feb 1 16 3 857-66

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PMID
20103683