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pubmed-article:20098695pubmed:abstractTextObesity is a worldwide epidemic, and severe obesity is a risk factor for many diseases, including diabetes, heart disease, stroke, and some cancers. Endocannabinoid system (ECS) signaling in the brain and peripheral tissues is activated in obesity and plays a role in the regulation of body weight. The main research question here was whether quantitative measurement of plasma endocannabinoids, anandamide, and related N-acylethanolamines (NAEs), combined with genotyping for mutations in fatty acid amide hydrolase (FAAH) would identify circulating biomarkers of ECS activation in severe obesity.lld:pubmed
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pubmed-article:20098695pubmed:articleTitleBiomarkers of endocannabinoid system activation in severe obesity.lld:pubmed
pubmed-article:20098695pubmed:affiliationDepartment of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, California, United States of America. jcsipe@scripps.edulld:pubmed
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