| pubmed-article:20085661 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20085661 | lifeskim:mentions | umls-concept:C0085104 | lld:lifeskim |
| pubmed-article:20085661 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:20085661 | lifeskim:mentions | umls-concept:C0004462 | lld:lifeskim |
| pubmed-article:20085661 | lifeskim:mentions | umls-concept:C0439855 | lld:lifeskim |
| pubmed-article:20085661 | lifeskim:mentions | umls-concept:C0205464 | lld:lifeskim |
| pubmed-article:20085661 | pubmed:dateCreated | 2010-3-12 | lld:pubmed |
| pubmed-article:20085661 | pubmed:abstractText | Targeted delivery of pharmaceutical agents into selected populations of CNS (Central Nervous System) neurons is an extremely compelling goal. Currently, systemic methods are generally used for delivery of pain medications, anti-virals for treatment of dermatomal infections, anti-spasmodics, and neuroprotectants. Systemic side effects or undesirable effects on parts of the CNS that are not involved in the pathology limit efficacy and limit clinical utility for many classes of pharmaceuticals. Axonal transport from the periphery offers a possible selective route, but there has been little progress towards design of agents that can accomplish targeted delivery via this intraneural route. To achieve this goal, we developed a tripartite molecular construction concept involving an axonal transport facilitator molecule, a polymer linker, and a large number of drug molecules conjugated to the linker, then sought to evaluate its neurobiology and pharmacological behavior. | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20085661 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:20085661 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20085661 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20085661 | pubmed:issn | 1471-2202 | lld:pubmed |
| pubmed-article:20085661 | pubmed:author | pubmed-author:HsuiY SYS | lld:pubmed |
| pubmed-article:20085661 | pubmed:author | pubmed-author:DabbyRR | lld:pubmed |
| pubmed-article:20085661 | pubmed:author | pubmed-author:GriffithsJohn... | lld:pubmed |
| pubmed-article:20085661 | pubmed:author | pubmed-author:HoweFranklyn... | lld:pubmed |
| pubmed-article:20085661 | pubmed:author | pubmed-author:BellB... | lld:pubmed |
| pubmed-article:20085661 | pubmed:author | pubmed-author:LeverAndrew... | lld:pubmed |
| pubmed-article:20085661 | pubmed:author | pubmed-author:FredericksonM... | lld:pubmed |
| pubmed-article:20085661 | pubmed:author | pubmed-author:WhitesideGart... | lld:pubmed |
| pubmed-article:20085661 | pubmed:author | pubmed-author:SokoloffAlan... | lld:pubmed |
| pubmed-article:20085661 | pubmed:author | pubmed-author:FillerAaron... | lld:pubmed |
| pubmed-article:20085661 | pubmed:author | pubmed-author:RabinowitzMir... | lld:pubmed |
