Alzheimer's-related endosome dysfunction in Down syndrome is Abeta-independent but requires APP and is reversed by BACE-1 inhibition.

Source:http://linkedlifedata.com/resource/pubmed/id/20080541

Proc. Natl. Acad. Sci. U.S.A. 2010 Jan 26 107 4 1630-5

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PMID
20080541