| pubmed-article:20075844 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20075844 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:20075844 | lifeskim:mentions | umls-concept:C1328818 | lld:lifeskim |
| pubmed-article:20075844 | lifeskim:mentions | umls-concept:C0003009 | lld:lifeskim |
| pubmed-article:20075844 | lifeskim:mentions | umls-concept:C0178719 | lld:lifeskim |
| pubmed-article:20075844 | lifeskim:mentions | umls-concept:C0033382 | lld:lifeskim |
| pubmed-article:20075844 | lifeskim:mentions | umls-concept:C0441889 | lld:lifeskim |
| pubmed-article:20075844 | lifeskim:mentions | umls-concept:C1120110 | lld:lifeskim |
| pubmed-article:20075844 | lifeskim:mentions | umls-concept:C1425435 | lld:lifeskim |
| pubmed-article:20075844 | lifeskim:mentions | umls-concept:C1710082 | lld:lifeskim |
| pubmed-article:20075844 | lifeskim:mentions | umls-concept:C0392760 | lld:lifeskim |
| pubmed-article:20075844 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:20075844 | pubmed:dateCreated | 2010-4-20 | lld:pubmed |
| pubmed-article:20075844 | pubmed:abstractText | A direct renin inhibitor (DRI) had a benefit in decreasing albuminuria in type 2 diabetic patients having already been treated with angiotensin (Ang) II type 1 receptor blocker (ARB), suggesting that aliskiren may have another effect other than blockade of the traditional renin-angiotensin system (RAS). Recently, prorenin bound to (pro)renin receptor ((P)RR) was found and shown to evoke two pathways; the generation of Ang peptides and the receptor-dependent activation of extracellular signal-related protein kinase (ERK). Because (P)RR is present in the podocytes, a central component of the glomerular filtration barrier, we hypothesized that aliskiren influences the (P)RR-induced two pathways in human podocytes. | lld:pubmed |
| pubmed-article:20075844 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20075844 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20075844 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20075844 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:20075844 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:20075844 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:20075844 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20075844 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20075844 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:20075844 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:20075844 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20075844 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20075844 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20075844 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20075844 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20075844 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20075844 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20075844 | pubmed:month | May | lld:pubmed |
| pubmed-article:20075844 | pubmed:issn | 1941-7225 | lld:pubmed |
| pubmed-article:20075844 | pubmed:author | pubmed-author:ItohHiroshiH | lld:pubmed |
| pubmed-article:20075844 | pubmed:author | pubmed-author:NishiyamaAkir... | lld:pubmed |
| pubmed-article:20075844 | pubmed:author | pubmed-author:SaleemMoin... | lld:pubmed |
| pubmed-article:20075844 | pubmed:author | pubmed-author:IchiharaAtsuh... | lld:pubmed |
| pubmed-article:20075844 | pubmed:author | pubmed-author:SuzukiFumiaki... | lld:pubmed |
| pubmed-article:20075844 | pubmed:author | pubmed-author:SakodaMariyoM | lld:pubmed |
| pubmed-article:20075844 | pubmed:author | pubmed-author:NaritaTatsuya... | lld:pubmed |
| pubmed-article:20075844 | pubmed:author | pubmed-author:Kurauchi-Mito... | lld:pubmed |
| pubmed-article:20075844 | pubmed:author | pubmed-author:KinouchiKenic... | lld:pubmed |
| pubmed-article:20075844 | pubmed:author | pubmed-author:Murohashi-Bok... | lld:pubmed |
| pubmed-article:20075844 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:20075844 | pubmed:volume | 23 | lld:pubmed |
| pubmed-article:20075844 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20075844 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20075844 | pubmed:pagination | 575-80 | lld:pubmed |
| pubmed-article:20075844 | pubmed:dateRevised | 2011-6-30 | lld:pubmed |
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| pubmed-article:20075844 | pubmed:meshHeading | pubmed-meshheading:20075844... | lld:pubmed |
| pubmed-article:20075844 | pubmed:meshHeading | pubmed-meshheading:20075844... | lld:pubmed |
| pubmed-article:20075844 | pubmed:meshHeading | pubmed-meshheading:20075844... | lld:pubmed |
| pubmed-article:20075844 | pubmed:meshHeading | pubmed-meshheading:20075844... | lld:pubmed |
| pubmed-article:20075844 | pubmed:meshHeading | pubmed-meshheading:20075844... | lld:pubmed |
| pubmed-article:20075844 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:20075844 | pubmed:articleTitle | Aliskiren inhibits intracellular angiotensin II levels without affecting (pro)renin receptor signals in human podocytes. | lld:pubmed |
| pubmed-article:20075844 | pubmed:affiliation | Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan. | lld:pubmed |
| pubmed-article:20075844 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:20075844 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:20075844 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:20075844 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:20075844 | lld:pubmed |
