| pubmed-article:20037963 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20037963 | lifeskim:mentions | umls-concept:C0030193 | lld:lifeskim |
| pubmed-article:20037963 | lifeskim:mentions | umls-concept:C1533685 | lld:lifeskim |
| pubmed-article:20037963 | lifeskim:mentions | umls-concept:C0003297 | lld:lifeskim |
| pubmed-article:20037963 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:20037963 | lifeskim:mentions | umls-concept:C0034957 | lld:lifeskim |
| pubmed-article:20037963 | lifeskim:mentions | umls-concept:C1871004 | lld:lifeskim |
| pubmed-article:20037963 | lifeskim:mentions | umls-concept:C1960929 | lld:lifeskim |
| pubmed-article:20037963 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:20037963 | pubmed:dateCreated | 2009-12-29 | lld:pubmed |
| pubmed-article:20037963 | pubmed:abstractText | Injection pain has been associated with veterinary use of the antiemetic maropitant (Cerenia, Pfizer Animal Health). Cerenia is formulated using sulphobutylether-beta-cyclodextrin to bind maropitant and mitigate injection pain. The objective of this study was to determine whether the temperature of Cerenia alters binding between maropitant and sulphobutylether-beta-cyclodextrin and affects injection pain. Binding decreased as temperature increased, and Cerenia-elicited injection pain increased at warmer drug temperatures. These data suggest that the amount of free unbound maropitant increases with temperature and that injection pain increases with temperature in a similar fashion. Clinically, these studies suggest that injection of refrigerated Cerenia may significantly reduce or eliminate pain associated with SC injection of Cerenia. | lld:pubmed |
| pubmed-article:20037963 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20037963 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20037963 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:20037963 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20037963 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20037963 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20037963 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20037963 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20037963 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20037963 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20037963 | pubmed:issn | 1528-3593 | lld:pubmed |
| pubmed-article:20037963 | pubmed:author | pubmed-author:GalvanBetsyB | lld:pubmed |
| pubmed-article:20037963 | pubmed:author | pubmed-author:McCallRobert... | lld:pubmed |
| pubmed-article:20037963 | pubmed:author | pubmed-author:NarishettySun... | lld:pubmed |
| pubmed-article:20037963 | pubmed:author | pubmed-author:CoscarelliEil... | lld:pubmed |
| pubmed-article:20037963 | pubmed:author | pubmed-author:AleoMichelleM | lld:pubmed |
| pubmed-article:20037963 | pubmed:author | pubmed-author:FleckTimT | lld:pubmed |
| pubmed-article:20037963 | pubmed:author | pubmed-author:HumphreyWilli... | lld:pubmed |
| pubmed-article:20037963 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:20037963 | pubmed:volume | 10 | lld:pubmed |
| pubmed-article:20037963 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20037963 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20037963 | pubmed:pagination | 93-102 | lld:pubmed |
| pubmed-article:20037963 | pubmed:meshHeading | pubmed-meshheading:20037963... | lld:pubmed |
| pubmed-article:20037963 | pubmed:meshHeading | pubmed-meshheading:20037963... | lld:pubmed |
| pubmed-article:20037963 | pubmed:meshHeading | pubmed-meshheading:20037963... | lld:pubmed |
| pubmed-article:20037963 | pubmed:meshHeading | pubmed-meshheading:20037963... | lld:pubmed |
| pubmed-article:20037963 | pubmed:meshHeading | pubmed-meshheading:20037963... | lld:pubmed |
| pubmed-article:20037963 | pubmed:meshHeading | pubmed-meshheading:20037963... | lld:pubmed |
| pubmed-article:20037963 | pubmed:meshHeading | pubmed-meshheading:20037963... | lld:pubmed |
| pubmed-article:20037963 | pubmed:meshHeading | pubmed-meshheading:20037963... | lld:pubmed |
| pubmed-article:20037963 | pubmed:meshHeading | pubmed-meshheading:20037963... | lld:pubmed |
| pubmed-article:20037963 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:20037963 | pubmed:articleTitle | Effect of refrigeration of the antiemetic Cerenia (maropitant) on pain on injection. | lld:pubmed |
| pubmed-article:20037963 | pubmed:affiliation | Pfizer Animal Health, Discovery Research, 7000 Portage Road, Kalamazoo, MI 49001, USA. | lld:pubmed |
| pubmed-article:20037963 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:20037963 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
| pubmed-article:20037963 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
