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pubmed-article:20022179pubmed:dateCreated2010-7-30lld:pubmed
pubmed-article:20022179pubmed:abstractTextIdentification of individual single wall nanotubes (SWNTs) within a cellular structure can provide vital information towards understanding the potential mechanisms of uptake, their localisation and whether their structure is transformed within a cell. To be able to image an individual SWNT in such an environment a resolution is required that is not usually appropriate for biological sections. Standard transmission electron microscopy (TEM) techniques such as bright field imaging of these cellular structures result in very weak contrast. Traditionally, researchers have stained the cells with heavy metal stains to enhance the cellular structure, however this can lead to confusion when analysing the samples at high resolution. Subsequently, alternative methods have been investigated to allow high resolution imaging and spectroscopy to identify SWNTs within the cell; here we will concentrate on the sample preparation and experimental methods used to achieve such resolution.lld:pubmed
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pubmed-article:20022179pubmed:issn1879-2723lld:pubmed
pubmed-article:20022179pubmed:authorpubmed-author:SkepperJeremy...lld:pubmed
pubmed-article:20022179pubmed:authorpubmed-author:MullerKarinKlld:pubmed
pubmed-article:20022179pubmed:authorpubmed-author:MidgleyPaul...lld:pubmed
pubmed-article:20022179pubmed:authorpubmed-author:PorterAlexand...lld:pubmed
pubmed-article:20022179pubmed:authorpubmed-author:GassMhairi...lld:pubmed
pubmed-article:20022179pubmed:authorpubmed-author:WellandMarkMlld:pubmed
pubmed-article:20022179pubmed:authorpubmed-author:BendallJames...lld:pubmed
pubmed-article:20022179pubmed:copyrightInfoCopyright 2009 Elsevier B.V. All rights reserved.lld:pubmed
pubmed-article:20022179pubmed:issnTypeElectroniclld:pubmed
pubmed-article:20022179pubmed:volume110lld:pubmed
pubmed-article:20022179pubmed:ownerNLMlld:pubmed
pubmed-article:20022179pubmed:authorsCompleteYlld:pubmed
pubmed-article:20022179pubmed:pagination946-51lld:pubmed
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pubmed-article:20022179pubmed:year2010lld:pubmed
pubmed-article:20022179pubmed:articleTitleCs corrected STEM EELS: Analysing beam sensitive carbon nanomaterials in cellular structures.lld:pubmed
pubmed-article:20022179pubmed:affiliationSuperSTEM, Daresbury Lab, Keckwick Lane, Daresbury WA4 4AD, UK. m.h.gass@liv.ac.uklld:pubmed
pubmed-article:20022179pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:20022179pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed