| pubmed-article:20018061 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20018061 | lifeskim:mentions | umls-concept:C0003873 | lld:lifeskim |
| pubmed-article:20018061 | lifeskim:mentions | umls-concept:C0020792 | lld:lifeskim |
| pubmed-article:20018061 | lifeskim:mentions | umls-concept:C1947915 | lld:lifeskim |
| pubmed-article:20018061 | lifeskim:mentions | umls-concept:C0205419 | lld:lifeskim |
| pubmed-article:20018061 | lifeskim:mentions | umls-concept:C0332281 | lld:lifeskim |
| pubmed-article:20018061 | lifeskim:mentions | umls-concept:C0314603 | lld:lifeskim |
| pubmed-article:20018061 | lifeskim:mentions | umls-concept:C0684321 | lld:lifeskim |
| pubmed-article:20018061 | lifeskim:mentions | umls-concept:C1707520 | lld:lifeskim |
| pubmed-article:20018061 | pubmed:dateCreated | 2009-12-18 | lld:pubmed |
| pubmed-article:20018061 | pubmed:abstractText | ABSTRACT : Using the North American Rheumatoid Arthritis Consortium genome-wide association dataset, we applied ridged, multiple least-squares regression to identify genetic variants with apparent unique contributions to variation of anti-cyclic citrullinated peptide (anti-CCP), a newly identified clinical risk factor for development of rheumatoid arthritis. Within a 2.7-Mbp region on chromosome 6 around the well studied HLA-DRB1 locus, ridge regression identified a single-nucleotide polymorphism that was associated with anti-CCP variation when including the additive effects of other single-nucleotide polymorphisms in a multivariable analysis, but that showed only a weak direct association with anti-CCP. This suggests that multivariable methods can be used to identify potentially relevant genetic variants in regions of interest that would be difficult to detect based on direct associations. | lld:pubmed |
| pubmed-article:20018061 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20018061 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20018061 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20018061 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20018061 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20018061 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20018061 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20018061 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20018061 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20018061 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20018061 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20018061 | pubmed:status | PubMed-not-MEDLINE | lld:pubmed |
| pubmed-article:20018061 | pubmed:issn | 1753-6561 | lld:pubmed |
| pubmed-article:20018061 | pubmed:author | pubmed-author:SheddenKerby... | lld:pubmed |
| pubmed-article:20018061 | pubmed:author | pubmed-author:ZhuJiJ | lld:pubmed |
| pubmed-article:20018061 | pubmed:author | pubmed-author:SunYan VYV | lld:pubmed |
| pubmed-article:20018061 | pubmed:author | pubmed-author:KardiaSharon... | lld:pubmed |
| pubmed-article:20018061 | pubmed:author | pubmed-author:ChoiNam-HeeNH | lld:pubmed |
| pubmed-article:20018061 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:20018061 | pubmed:volume | 3 Suppl 7 | lld:pubmed |
| pubmed-article:20018061 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20018061 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20018061 | pubmed:pagination | S67 | lld:pubmed |
| pubmed-article:20018061 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:20018061 | pubmed:articleTitle | Identification of correlated genetic variants jointly associated with rheumatoid arthritis using ridge regression. | lld:pubmed |
| pubmed-article:20018061 | pubmed:affiliation | Department of Epidemiology, School of Public Health, University of Michigan, 109 Observatory, Ann Arbor, Michigan 48109, USA. yansun@umich.edu. | lld:pubmed |
| pubmed-article:20018061 | pubmed:publicationType | Journal Article | lld:pubmed |
