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pubmed-article:2001468pubmed:abstractTextAutologous blood placed around the basilar artery caused angiographic narrowing with a biphasic time course. The first immediate phase was reversed by intraarterial papaverine; the second exhibited an increasing component of narrowing which was papaverine-resistant. In vitro studies showed that vessels became increasingly stiffer, less capable to develop active tone, and less responsive to vasoconstrictors and vasodilators. The papaverine-resistant component of angiographic narrowing (in vivo) could be directly correlated with loss of contractility and increased artery wall stiffness (in vitro).lld:pubmed
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pubmed-article:2001468pubmed:articleTitleTwo indices of functional damage of the artery wall parallel the time course of irreversible narrowing in experimental vasospasm in the rabbit.lld:pubmed
pubmed-article:2001468pubmed:affiliationVermont Center for Vascular Research, University of Vermont, Burlington.lld:pubmed
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