Linked Life Data

20010449

Source:http://linkedlifedata.com/resource/pubmed/id/20010449

Statements in which the resource exists.
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pubmed-article:20010449pubmed:abstractTextDisturbances in central serotonin function have been implicated in impulsive and aggressive behavior. A deletion/insertion polymorphism within the 5-HT transporter promoter gene (5-HTTLPR) is thought to be associated with disturbed impulse control, anxiety, and depression. The serotonin transporter (5-HTT) is the primary action site for selective serotonin reuptake inhibitors (SSRIs). Several studies of major depression have shown that the l allele of 5-HTTLPR is associated with better SSRI antidepressant effects than the s allele.lld:pubmed
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pubmed-article:20010449pubmed:articleTitleFluoxetine response in impulsive-aggressive behavior and serotonin transporter polymorphism in personality disorder.lld:pubmed
pubmed-article:20010449pubmed:affiliationPsychiatric Clinic of University of Chile, Santiago de Chile, Chile. hsilva@med.uchile.cllld:pubmed
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