| pubmed-article:19957083 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19957083 | lifeskim:mentions | umls-concept:C0020792 | lld:lifeskim |
| pubmed-article:19957083 | lifeskim:mentions | umls-concept:C0080194 | lld:lifeskim |
| pubmed-article:19957083 | lifeskim:mentions | umls-concept:C2718003 | lld:lifeskim |
| pubmed-article:19957083 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:19957083 | pubmed:dateCreated | 2010-1-21 | lld:pubmed |
| pubmed-article:19957083 | pubmed:abstractText | Avermectins produced by Streptomyces avermitilis are potent against a broad spectrum of nematode and arthropod parasites with low-level side effects on the host organisms. This study was designed to investigate a high-throughput screening strategy for the efficient identification of avermectin high-yield strains. The production protocol was miniaturized in 96 deep-well microplates. UV absorbance at 245 nm was used to monitor avermectin production. A good correlation between fermentation results in both 96 deep-well microplates and conventional Erlenmeyer flasks was observed. With this protocol, the production of avermectins was determined in less than 10 min for a full plate without compromising accuracy. The high-yield strain selected through this protocol was also tested in 360 m(3) batch fermentation with 1.6-fold improved outcome. Thus, the development of this protocol is expected to accelerate the selection of superior avermectin-producing strains. | lld:pubmed |
| pubmed-article:19957083 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19957083 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19957083 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19957083 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19957083 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19957083 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19957083 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:19957083 | pubmed:issn | 1432-0614 | lld:pubmed |
| pubmed-article:19957083 | pubmed:author | pubmed-author:RAOS VSV | lld:pubmed |
| pubmed-article:19957083 | pubmed:author | pubmed-author:ZhangLixinL | lld:pubmed |
| pubmed-article:19957083 | pubmed:author | pubmed-author:GaoHongH | lld:pubmed |
| pubmed-article:19957083 | pubmed:author | pubmed-author:XuBingB | lld:pubmed |
| pubmed-article:19957083 | pubmed:author | pubmed-author:LiuXiangyangX | lld:pubmed |
| pubmed-article:19957083 | pubmed:author | pubmed-author:ChenXiaopingX | lld:pubmed |
| pubmed-article:19957083 | pubmed:author | pubmed-author:ZhuoYingY | lld:pubmed |
| pubmed-article:19957083 | pubmed:author | pubmed-author:GouZhongxuanZ | lld:pubmed |
| pubmed-article:19957083 | pubmed:author | pubmed-author:ZhangWenquanW | lld:pubmed |
| pubmed-article:19957083 | pubmed:author | pubmed-author:ZhengChuansen... | lld:pubmed |
| pubmed-article:19957083 | pubmed:author | pubmed-author:LiuJintaoJ | lld:pubmed |
| pubmed-article:19957083 | pubmed:author | pubmed-author:ZhouXianlongX | lld:pubmed |
| pubmed-article:19957083 | pubmed:author | pubmed-author:LuoAiqunA | lld:pubmed |
| pubmed-article:19957083 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19957083 | pubmed:volume | 85 | lld:pubmed |
| pubmed-article:19957083 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19957083 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19957083 | pubmed:pagination | 1219-25 | lld:pubmed |
| pubmed-article:19957083 | pubmed:meshHeading | pubmed-meshheading:19957083... | lld:pubmed |
| pubmed-article:19957083 | pubmed:meshHeading | pubmed-meshheading:19957083... | lld:pubmed |
| pubmed-article:19957083 | pubmed:meshHeading | pubmed-meshheading:19957083... | lld:pubmed |
| pubmed-article:19957083 | pubmed:meshHeading | pubmed-meshheading:19957083... | lld:pubmed |
| pubmed-article:19957083 | pubmed:meshHeading | pubmed-meshheading:19957083... | lld:pubmed |
| pubmed-article:19957083 | pubmed:meshHeading | pubmed-meshheading:19957083... | lld:pubmed |
| pubmed-article:19957083 | pubmed:meshHeading | pubmed-meshheading:19957083... | lld:pubmed |
| pubmed-article:19957083 | pubmed:meshHeading | pubmed-meshheading:19957083... | lld:pubmed |
| pubmed-article:19957083 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:19957083 | pubmed:articleTitle | Identification of avermectin-high-producing strains by high-throughput screening methods. | lld:pubmed |
| pubmed-article:19957083 | pubmed:affiliation | Institute of Microbiology, Chinese Academy of Sciences (CAS), Beijing, People's Republic of China. | lld:pubmed |
| pubmed-article:19957083 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19957083 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:19957083 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:19957083 | pubmed:publicationType | Evaluation Studies | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:19957083 | lld:pubmed |
