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pubmed-article:19953182pubmed:abstractTextLow-coherence spectroscopy (LCS) is a spectroscopic method that allows for quantitative and localized assessment of absorption spectra by combining reflection spectroscopy with low-coherence interferometry. We describe absorption coefficient (mu(a)) measurements by LCS in tissue simulating phantoms with varying scattering and absorbing properties. We used LCS in the 455-680 nm wavelength range with a spectral resolution of 8 nm to obtain mu(a) spectra with +/-0.5 mm(-1) accuracy. We conclude that LCS is a promising technique for the in vivo determination of tissue chromophore concentrations.lld:pubmed
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pubmed-article:19953182pubmed:authorpubmed-author:FaberDirk JDJlld:pubmed
pubmed-article:19953182pubmed:authorpubmed-author:BosschaartNie...lld:pubmed
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pubmed-article:19953182pubmed:volume34lld:pubmed
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pubmed-article:19953182pubmed:pagination3746-8lld:pubmed
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pubmed-article:19953182pubmed:year2009lld:pubmed
pubmed-article:19953182pubmed:articleTitleQuantitative measurements of absorption spectra in scattering media by low-coherence spectroscopy.lld:pubmed
pubmed-article:19953182pubmed:affiliationBiomedical Engineering and Physics, Academic Medical Center, University of Amsterdam, P.O. Box 22700,NL-1100 DE Amsterdam, The Netherlands. n.bosschaart@amc.uva.nllld:pubmed
pubmed-article:19953182pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:19953182pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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