| pubmed-article:19938959 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19938959 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:19938959 | lifeskim:mentions | umls-concept:C0011923 | lld:lifeskim |
| pubmed-article:19938959 | lifeskim:mentions | umls-concept:C0037868 | lld:lifeskim |
| pubmed-article:19938959 | lifeskim:mentions | umls-concept:C0005516 | lld:lifeskim |
| pubmed-article:19938959 | lifeskim:mentions | umls-concept:C0016263 | lld:lifeskim |
| pubmed-article:19938959 | lifeskim:mentions | umls-concept:C2348042 | lld:lifeskim |
| pubmed-article:19938959 | pubmed:issue | 5-6 | lld:pubmed |
| pubmed-article:19938959 | pubmed:dateCreated | 2009-11-26 | lld:pubmed |
| pubmed-article:19938959 | pubmed:abstractText | Spermatid specific thioredoxin-3 protein (SPTRX-3) accumulates in the superfluous cytoplasm of defective human spermatozoa. Novel ImageStream technology combining flow cytometry with cell imaging was used for parallel quantification and visualization of SPTRX-3 protein in defective spermatozoa of five men from infertile couples. The majority of the SPTRX-3 containing cells were overwhelmingly spermatozoa with a variety of morphological defects, detectable in the ImageStream recorded images. Quantitative parameters of relative SPTRX-3 induced fluorescence measured by ImageStream correlated closely with conventional flow cytometric measurements of the same sample set and reflected the results of clinical semen evaluation. Image Stream quantification of SPTRX-3 combines and surpasses the informative value of both conventional flow cytometry and light microscopic semen evaluation. The observed patterns of the retention of SPTRX-3 in the sperm samples from infertility patients support the view that SPTRX3 is a biomarker of male infertility. | lld:pubmed |
| pubmed-article:19938959 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19938959 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19938959 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19938959 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19938959 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19938959 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19938959 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19938959 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:19938959 | pubmed:issn | 1939-6376 | lld:pubmed |
| pubmed-article:19938959 | pubmed:author | pubmed-author:SutovskyPeter... | lld:pubmed |
| pubmed-article:19938959 | pubmed:author | pubmed-author:MorrisseyPhil... | lld:pubmed |
| pubmed-article:19938959 | pubmed:author | pubmed-author:Miranda-Vizue... | lld:pubmed |
| pubmed-article:19938959 | pubmed:author | pubmed-author:GeorgeThaddeu... | lld:pubmed |
| pubmed-article:19938959 | pubmed:author | pubmed-author:SutovskyMiria... | lld:pubmed |
| pubmed-article:19938959 | pubmed:author | pubmed-author:OzanonChristo... | lld:pubmed |
| pubmed-article:19938959 | pubmed:author | pubmed-author:FriendSherree... | lld:pubmed |
| pubmed-article:19938959 | pubmed:author | pubmed-author:BuckmanClayto... | lld:pubmed |
| pubmed-article:19938959 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19938959 | pubmed:volume | 55 | lld:pubmed |
| pubmed-article:19938959 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19938959 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19938959 | pubmed:pagination | 244-51 | lld:pubmed |
| pubmed-article:19938959 | pubmed:meshHeading | pubmed-meshheading:19938959... | lld:pubmed |
| pubmed-article:19938959 | pubmed:meshHeading | pubmed-meshheading:19938959... | lld:pubmed |
| pubmed-article:19938959 | pubmed:meshHeading | pubmed-meshheading:19938959... | lld:pubmed |
| pubmed-article:19938959 | pubmed:meshHeading | pubmed-meshheading:19938959... | lld:pubmed |
| pubmed-article:19938959 | pubmed:meshHeading | pubmed-meshheading:19938959... | lld:pubmed |
| pubmed-article:19938959 | pubmed:meshHeading | pubmed-meshheading:19938959... | lld:pubmed |
| pubmed-article:19938959 | pubmed:meshHeading | pubmed-meshheading:19938959... | lld:pubmed |
| pubmed-article:19938959 | pubmed:meshHeading | pubmed-meshheading:19938959... | lld:pubmed |
| pubmed-article:19938959 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:19938959 | pubmed:articleTitle | High throughput, parallel imaging and biomarker quantification of human spermatozoa by ImageStream flow cytometry. | lld:pubmed |
| pubmed-article:19938959 | pubmed:affiliation | Division of Animal Sciences, University of Missouri, Columbia, MO 65211-5300, USA. | lld:pubmed |
| pubmed-article:19938959 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19938959 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
