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pubmed-article:19938872pubmed:abstractTextThe present study tested the long-term effects of dietary kudzu root extract supplementation on the regulation of arterial pressure, plasma glucose, and circulating cholesterol in stroke-prone spontaneously hypertensive rats (SP-SHR). Female SP-SHR were maintained for 2 months on a polyphenol-free diet, with or without the addition of 0.2% kudzu root extract. Half of the rats in each diet group were ovariectomized, whereas the other half remained intact. Following 2 months on the diets, the 0.2% kudzu root extract supplementation (compared to control diet) significantly lowered arterial pressure (11-15 mmHg), plasma cholesterol, fasting blood glucose (20-30%), and fasting plasma insulin in both the ovariectomized and intact SP-SHR. These results indicate that long-term dietary kudzu root extract supplementation can improve glucose, lipid, and blood pressure control in intact and ovariectomized SP-SHR.lld:pubmed
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pubmed-article:19938872pubmed:articleTitleChronic dietary kudzu isoflavones improve components of metabolic syndrome in stroke-prone spontaneously hypertensive rats.lld:pubmed
pubmed-article:19938872pubmed:affiliationDepartment of Cell Biology, University of Alabama at Birmingham, Birmingham, Alabama 35294-0006, USA.lld:pubmed
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pubmed-article:19938872pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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