A program of systematic serology screening for toxoplasmosis during pregnancy has been running in France since 1978. The program involves monthly follow-ups for all non-immune pregnant women. Due to the steady decline in the seroprevalence of toxoplasmosis, the cost of the program is steadily increasing. Current screening is based on the detection of IgG and IgM isotypes. The aim of this work was to estimate the benefit of replacing combined dosage of two isotypes, by an alternative strategy that detects total anti-Toxoplasma immunoglobulins.
Laboratoire de parasitologie-mycologie, hôpital Cochin, faculté de médecine Paris-Descartes, 27, rue du Faubourg-Saint-Jacques, 75014 Paris, France. thierry.ancelle@parisdescartes.fr
