| pubmed-article:19926575 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19926575 | lifeskim:mentions | umls-concept:C0206687 | lld:lifeskim |
| pubmed-article:19926575 | lifeskim:mentions | umls-concept:C0227843 | lld:lifeskim |
| pubmed-article:19926575 | lifeskim:mentions | umls-concept:C0205065 | lld:lifeskim |
| pubmed-article:19926575 | lifeskim:mentions | umls-concept:C0038952 | lld:lifeskim |
| pubmed-article:19926575 | lifeskim:mentions | umls-concept:C1522602 | lld:lifeskim |
| pubmed-article:19926575 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:19926575 | lifeskim:mentions | umls-concept:C1419781 | lld:lifeskim |
| pubmed-article:19926575 | lifeskim:mentions | umls-concept:C0220901 | lld:lifeskim |
| pubmed-article:19926575 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:19926575 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:19926575 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:19926575 | pubmed:dateCreated | 2009-11-20 | lld:pubmed |
| pubmed-article:19926575 | pubmed:abstractText | We sought to investigate the expression levels of S100A1 in ovarian cancer cell lines and tissues to correlate S100A1 with subtype, stage, grade, and relapse-free survival. S100A1 messenger RNA and protein were up-regulated in ovarian cancer cell lines and tumors compared with normal ovarian cell lines and tissues by gene microarray analysis, reverse transcriptase-polymerase chain reaction, quantitative reverse transcriptase-polymerase chain reaction, and Western immunoblotting. In the study, 63.7% of serous, 21.2% of clear cell, 11.2% of endometrioid, and 3% of mucinous ovarian (1/31) cancers were S100A1+ by immunohistochemical staining of tissue microarrays (n = 500). S100A1 expression increased with increasing Silverberg grade but not stage in serous tumors. Endometrial tissue microarrays (n = 127) were 9.4% S100A1+; no correlation with stage or grade and S100A1 was found. In the endometrioid subtype of ovarian and endometrial cancers, relapse-free survival was decreased for patients with S100A1+ tumors. These data suggest that S100A1 is a marker for poor prognosis of endometrioid subtypes of cancer. | lld:pubmed |
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| pubmed-article:19926575 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19926575 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19926575 | pubmed:citationSubset | AIM | lld:pubmed |
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| pubmed-article:19926575 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19926575 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:19926575 | pubmed:issn | 1943-7722 | lld:pubmed |
| pubmed-article:19926575 | pubmed:author | pubmed-author:SkubitzAmy... | lld:pubmed |
| pubmed-article:19926575 | pubmed:author | pubmed-author:ArgentaPeter... | lld:pubmed |
| pubmed-article:19926575 | pubmed:author | pubmed-author:PambuccianSte... | lld:pubmed |
| pubmed-article:19926575 | pubmed:author | pubmed-author:BoylanKristin... | lld:pubmed |
| pubmed-article:19926575 | pubmed:author | pubmed-author:KallogerSteve... | lld:pubmed |
| pubmed-article:19926575 | pubmed:author | pubmed-author:DeRyckeMeliss... | lld:pubmed |
| pubmed-article:19926575 | pubmed:author | pubmed-author:AndersenJohn... | lld:pubmed |
| pubmed-article:19926575 | pubmed:author | pubmed-author:HarringtonKat... | lld:pubmed |
| pubmed-article:19926575 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19926575 | pubmed:volume | 132 | lld:pubmed |
| pubmed-article:19926575 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19926575 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19926575 | pubmed:pagination | 846-56 | lld:pubmed |
| pubmed-article:19926575 | pubmed:dateRevised | 2011-7-25 | lld:pubmed |
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