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pubmed-article:19914648pubmed:abstractTextIn the classic view of bladder development the trigone originates from the mesoderm derived wolffian ducts while the remainder of the bladder originates from the endoderm derived urogenital sinus. Recent molecular developmental studies have questioned the veracity of this received wisdom, suggesting an endodermal origin for the trigone. To shed further light on this issue we observed mesenchymal-epithelial interactions between trigone epithelium and fetal urogenital sinus mesenchyma to infer the trigonal germ layer of origin.lld:pubmed
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pubmed-article:19914648pubmed:dateRevised2011-9-26lld:pubmed
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pubmed-article:19914648pubmed:articleTitleEndodermal origin of bladder trigone inferred from mesenchymal-epithelial interaction.lld:pubmed
pubmed-article:19914648pubmed:affiliationDepartment of Urologic Surgery, Monroe Carell, Jr Children's Hospital at Vanderbilt, Nashville, Tennessee 37232-9820, USA. stacy.tanaka@vanderbilt.edulld:pubmed
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