| pubmed-article:199018 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:199018 | lifeskim:mentions | umls-concept:C0205474 | lld:lifeskim |
| pubmed-article:199018 | lifeskim:mentions | umls-concept:C0023516 | lld:lifeskim |
| pubmed-article:199018 | lifeskim:mentions | umls-concept:C0007965 | lld:lifeskim |
| pubmed-article:199018 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:199018 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:199018 | pubmed:dateCreated | 1977-11-25 | lld:pubmed |
| pubmed-article:199018 | pubmed:abstractText | Blood leukocytes from a patient with Chediak-Higashi syndrome (CHS) were compared with normal cells for their capacity of extruding (exocytosis) the lysosomal enzyme myeloperoxidase during phagocytosis or after a treatment with the ionophore A23187 and Ca2+. A decreased rate and extent of exocytosis in phagocytizing CHS cells was observed also with the Ca2+ ionophore. This suggests that a defect in Ca2+ mobilization is not responsible for the impaired secretion of granule content. Isolated granules of CHS cells and of leukocytes were treated with the detergent Triton X-100. Since the solubilization of myeloperoxidase from the CHS granules was much lower than from the normal ones, we suggest that the former organelles have a more resistant membrane. | lld:pubmed |
| pubmed-article:199018 | pubmed:language | eng | lld:pubmed |
| pubmed-article:199018 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:199018 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:199018 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:199018 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:199018 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:199018 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:199018 | pubmed:issn | 0001-5792 | lld:pubmed |
| pubmed-article:199018 | pubmed:author | pubmed-author:PanizonFF | lld:pubmed |
| pubmed-article:199018 | pubmed:author | pubmed-author:CramerRR | lld:pubmed |
| pubmed-article:199018 | pubmed:author | pubmed-author:ZabucchiGG | lld:pubmed |
| pubmed-article:199018 | pubmed:author | pubmed-author:SoranzoM RMR | lld:pubmed |
| pubmed-article:199018 | pubmed:author | pubmed-author:TamaroPP | lld:pubmed |
| pubmed-article:199018 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:199018 | pubmed:volume | 58 | lld:pubmed |
| pubmed-article:199018 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:199018 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:199018 | pubmed:pagination | 50-7 | lld:pubmed |
| pubmed-article:199018 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
| pubmed-article:199018 | pubmed:meshHeading | pubmed-meshheading:199018-H... | lld:pubmed |
| pubmed-article:199018 | pubmed:meshHeading | pubmed-meshheading:199018-P... | lld:pubmed |
| pubmed-article:199018 | pubmed:meshHeading | pubmed-meshheading:199018-L... | lld:pubmed |
| pubmed-article:199018 | pubmed:meshHeading | pubmed-meshheading:199018-P... | lld:pubmed |
| pubmed-article:199018 | pubmed:meshHeading | pubmed-meshheading:199018-C... | lld:pubmed |
| pubmed-article:199018 | pubmed:meshHeading | pubmed-meshheading:199018-F... | lld:pubmed |
| pubmed-article:199018 | pubmed:meshHeading | pubmed-meshheading:199018-P... | lld:pubmed |
| pubmed-article:199018 | pubmed:meshHeading | pubmed-meshheading:199018-C... | lld:pubmed |
| pubmed-article:199018 | pubmed:meshHeading | pubmed-meshheading:199018-E... | lld:pubmed |
| pubmed-article:199018 | pubmed:meshHeading | pubmed-meshheading:199018-C... | lld:pubmed |
| pubmed-article:199018 | pubmed:year | 1977 | lld:pubmed |
| pubmed-article:199018 | pubmed:articleTitle | Biochemical studies on the leukocytes in Chediak-Higashi syndrome. | lld:pubmed |
| pubmed-article:199018 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:199018 | pubmed:publicationType | Case Reports | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:199018 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:199018 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:199018 | lld:pubmed |
