pubmed-article:19851034 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:19851034 | lifeskim:mentions | umls-concept:C0007600 | lld:lifeskim |
pubmed-article:19851034 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
pubmed-article:19851034 | lifeskim:mentions | umls-concept:C0238463 | lld:lifeskim |
pubmed-article:19851034 | lifeskim:mentions | umls-concept:C1518174 | lld:lifeskim |
pubmed-article:19851034 | lifeskim:mentions | umls-concept:C1101610 | lld:lifeskim |
pubmed-article:19851034 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
pubmed-article:19851034 | lifeskim:mentions | umls-concept:C1548673 | lld:lifeskim |
pubmed-article:19851034 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
pubmed-article:19851034 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
pubmed-article:19851034 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:19851034 | pubmed:dateCreated | 2010-1-29 | lld:pubmed |
pubmed-article:19851034 | pubmed:abstractText | The purpose of these studies was to explore the expression pattern of miRNAs associated with invasion and metastasis of human papillary thyroid carcinoma (PTC). A transwell invasion chamber was used to select progressively more invasive cancer cell populations from a clonal cell line of human PTC with cervical lymph node metastasis, IHH-4. Three sublines with progressive invasiveness, designated IHH-4M-1, IHH-4M-2 and IHH-4M-3, were obtained through this in vitro selection process. The sublines manifested an increase in colony-forming ability on soft agar and metastatic potency in nude mice. Then metastasis-related miRNAs differentially expressed between them were analyzed utilizing the miRNA microarray technique. We found that 11 metastasis-related miRNAs were differentially expressed between the invasive subpopulations and their control subpopulations; these miRNAs may account for their significant difference in the invasion capabilities and favor lymphatic metastasis of PTC. | lld:pubmed |
pubmed-article:19851034 | pubmed:language | eng | lld:pubmed |
pubmed-article:19851034 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:19851034 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:19851034 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:19851034 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:19851034 | pubmed:issn | 1348-4540 | lld:pubmed |
pubmed-article:19851034 | pubmed:author | pubmed-author:WangHongH | lld:pubmed |
pubmed-article:19851034 | pubmed:author | pubmed-author:ZhangHongmeiH | lld:pubmed |
pubmed-article:19851034 | pubmed:author | pubmed-author:GaoYunY | lld:pubmed |
pubmed-article:19851034 | pubmed:author | pubmed-author:TengWeipingW | lld:pubmed |
pubmed-article:19851034 | pubmed:author | pubmed-author:ShanZhongyanZ | lld:pubmed |
pubmed-article:19851034 | pubmed:author | pubmed-author:GuanHaixiaH | lld:pubmed |
pubmed-article:19851034 | pubmed:author | pubmed-author:FanChenlingC | lld:pubmed |
pubmed-article:19851034 | pubmed:author | pubmed-author:MaoJinyuanJ | lld:pubmed |
pubmed-article:19851034 | pubmed:author | pubmed-author:WangCuifangC | lld:pubmed |
pubmed-article:19851034 | pubmed:issnType | Electronic | lld:pubmed |
pubmed-article:19851034 | pubmed:volume | 57 | lld:pubmed |
pubmed-article:19851034 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:19851034 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:19851034 | pubmed:pagination | 81-6 | lld:pubmed |
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pubmed-article:19851034 | pubmed:year | 2010 | lld:pubmed |
pubmed-article:19851034 | pubmed:articleTitle | miRNA expression in a human papillary thyroid carcinoma cell line varies with invasiveness. | lld:pubmed |
pubmed-article:19851034 | pubmed:affiliation | Endocrine Department and Institute of Endocrinology, First Affiliated Hospital of China Medical University, Shenyang, China. | lld:pubmed |
pubmed-article:19851034 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:19851034 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |