Linked Life Data

19849988

Source:http://linkedlifedata.com/resource/pubmed/id/19849988

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pubmed-article:19849988pubmed:abstractTextThrombolysis remains the main therapeutic strategy used in stroke, but with a limited use to only a part of stroke patients. A neuroprotective approach would be necessary with a double objective : (1) to serve as an add-on treatment with thrombolysis to improve safety and increase therapeutic window ; (2) to limit infarct area by delaying neuronal death. While numerous molecules failed in clinical trials in stroke, pharmacological development is on-going with pleiotropic drugs targeting both neuronal and vascular parts of neurovascular unit. Another approach targets the functional rehabilitation and the neurorepair using pharmacological ways or cell therapy.lld:pubmed
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pubmed-article:19849988pubmed:articleTitle[Cerebral ischaemia: tomorrow's therapeutic tracks].lld:pubmed
pubmed-article:19849988pubmed:affiliationEA1046, département de pharmacologie médicale, Institut de médecine prédictive et de recherche thérapeutique, Université Lille-Nord de France, Faculté de médecine, Centre hospitalier et universitaire de Lille, 2, avenue Oscar Lambret 59037 Lille Cedex, France. r-bordet@chru-lille.frlld:pubmed
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