| pubmed-article:19839013 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19839013 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:19839013 | lifeskim:mentions | umls-concept:C0014544 | lld:lifeskim |
| pubmed-article:19839013 | lifeskim:mentions | umls-concept:C0087140 | lld:lifeskim |
| pubmed-article:19839013 | lifeskim:mentions | umls-concept:C0006104 | lld:lifeskim |
| pubmed-article:19839013 | lifeskim:mentions | umls-concept:C0311400 | lld:lifeskim |
| pubmed-article:19839013 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:19839013 | lifeskim:mentions | umls-concept:C1511524 | lld:lifeskim |
| pubmed-article:19839013 | lifeskim:mentions | umls-concept:C1707520 | lld:lifeskim |
| pubmed-article:19839013 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:19839013 | pubmed:dateCreated | 2010-3-1 | lld:pubmed |
| pubmed-article:19839013 | pubmed:abstractText | The correlation and the interactions between neuronal activity and underlying metabolic dynamics are still a matter of debate, especially in pathological conditions. This study reports findings obtained on a subject suffering from fixation-off sensitivity (FOS) epilepsy, exploited as a model system of triggerable anomalous electrical activity. Functional Magnetic Resonance Spectroscopy was used to investigate the metabolic response to visual spike-inducing stimuli in a single voxel placed in the temporo-occipital lobe of a FOS epilepsy patient. MRS measurements were additionally performed on a control group of five healthy volunteers. The FOS patient also underwent an EEG session with the same stimulus paradigm. Uniquely in the FOS patient, glutamate and glutamine concentration increased during the first 10 min of stimulation and then returned to baseline. On the other hand, FOS-induced epileptic activity (spiking) endured throughout all the stimulation epoch. The observed metabolic dynamics may be likely linked to a complex interplay between alterations of the metabolic pathways of glutamate and modulation of the neuronal activity. | lld:pubmed |
| pubmed-article:19839013 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19839013 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19839013 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19839013 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19839013 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19839013 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:19839013 | pubmed:issn | 1099-1492 | lld:pubmed |
| pubmed-article:19839013 | pubmed:author | pubmed-author:ManfrediMario... | lld:pubmed |
| pubmed-article:19839013 | pubmed:author | pubmed-author:AprileTeresaT | lld:pubmed |
| pubmed-article:19839013 | pubmed:author | pubmed-author:HagbergGisela... | lld:pubmed |
| pubmed-article:19839013 | pubmed:author | pubmed-author:Di... | lld:pubmed |
| pubmed-article:19839013 | pubmed:author | pubmed-author:GiallonardoAn... | lld:pubmed |
| pubmed-article:19839013 | pubmed:author | pubmed-author:MaravigliaBru... | lld:pubmed |
| pubmed-article:19839013 | pubmed:author | pubmed-author:GarreffaGirol... | lld:pubmed |
| pubmed-article:19839013 | pubmed:author | pubmed-author:GioveFederico... | lld:pubmed |
| pubmed-article:19839013 | pubmed:author | pubmed-author:CarnìMarcoM | lld:pubmed |
| pubmed-article:19839013 | pubmed:author | pubmed-author:MangiaSilviaS | lld:pubmed |
| pubmed-article:19839013 | pubmed:author | pubmed-author:PecaStefanoS | lld:pubmed |
| pubmed-article:19839013 | pubmed:copyrightInfo | (c) 2009 John Wiley & Sons, Ltd. | lld:pubmed |
| pubmed-article:19839013 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19839013 | pubmed:volume | 23 | lld:pubmed |
| pubmed-article:19839013 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19839013 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19839013 | pubmed:pagination | 170-8 | lld:pubmed |
| pubmed-article:19839013 | pubmed:meshHeading | pubmed-meshheading:19839013... | lld:pubmed |
| pubmed-article:19839013 | pubmed:meshHeading | pubmed-meshheading:19839013... | lld:pubmed |
| pubmed-article:19839013 | pubmed:meshHeading | pubmed-meshheading:19839013... | lld:pubmed |
| pubmed-article:19839013 | pubmed:meshHeading | pubmed-meshheading:19839013... | lld:pubmed |
| pubmed-article:19839013 | pubmed:meshHeading | pubmed-meshheading:19839013... | lld:pubmed |
| pubmed-article:19839013 | pubmed:meshHeading | pubmed-meshheading:19839013... | lld:pubmed |
| pubmed-article:19839013 | pubmed:meshHeading | pubmed-meshheading:19839013... | lld:pubmed |
| pubmed-article:19839013 | pubmed:meshHeading | pubmed-meshheading:19839013... | lld:pubmed |
| pubmed-article:19839013 | pubmed:meshHeading | pubmed-meshheading:19839013... | lld:pubmed |
| pubmed-article:19839013 | pubmed:meshHeading | pubmed-meshheading:19839013... | lld:pubmed |
| pubmed-article:19839013 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:19839013 | pubmed:articleTitle | Metabolic correlatives of brain activity in a FOS epilepsy patient. | lld:pubmed |
| pubmed-article:19839013 | pubmed:affiliation | MARBILab, Museo storico della fisica e Centro di studi e ricerche Enrico Fermi, c/o Fondazione Santa Lucia IRCCS, 00179 Roma, Italy. | lld:pubmed |
| pubmed-article:19839013 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19839013 | pubmed:publicationType | Case Reports | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:19839013 | lld:pdb |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:19839013 | lld:pdb |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:19839013 | lld:pdb |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:19839013 | lld:pdb |
