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pubmed-article:19819427pubmed:abstractTextTreatment-resistant depression presents a serious challenge to both patients and clinicians. The anterior and midlateral prefrontal cortices play complementary roles in integrating emotional and cognitive experiences and in modulating subcortical regions. Both regions offer a distinct opportunity for targeted antidepressant treatments. We chose to pilot the safety and therapeutic benefits of chronic and intermittent epidural prefrontal cortical stimulation (EpCS) in patients with treatment-resistant depression.lld:pubmed
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pubmed-article:19819427pubmed:articleTitleBilateral epidural prefrontal cortical stimulation for treatment-resistant depression.lld:pubmed
pubmed-article:19819427pubmed:affiliationDepartment of Psychiatry, Mood Disorders Program and Brain Stimulation Laboratory, Medical University of South Carolina, Charleston, South Carolina, USA. nahasz@musc.edulld:pubmed
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