| pubmed-article:19751683 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19751683 | lifeskim:mentions | umls-concept:C0302523 | lld:lifeskim |
| pubmed-article:19751683 | lifeskim:mentions | umls-concept:C0700325 | lld:lifeskim |
| pubmed-article:19751683 | lifeskim:mentions | umls-concept:C0439851 | lld:lifeskim |
| pubmed-article:19751683 | lifeskim:mentions | umls-concept:C1257867 | lld:lifeskim |
| pubmed-article:19751683 | lifeskim:mentions | umls-concept:C0185026 | lld:lifeskim |
| pubmed-article:19751683 | lifeskim:mentions | umls-concept:C1706185 | lld:lifeskim |
| pubmed-article:19751683 | lifeskim:mentions | umls-concept:C1552596 | lld:lifeskim |
| pubmed-article:19751683 | lifeskim:mentions | umls-concept:C1947931 | lld:lifeskim |
| pubmed-article:19751683 | lifeskim:mentions | umls-concept:C0341662 | lld:lifeskim |
| pubmed-article:19751683 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:19751683 | pubmed:dateCreated | 2009-9-15 | lld:pubmed |
| pubmed-article:19751683 | pubmed:abstractText | The protein lambda(6-85) has been implicated in barrierless folding by observations of kinetic relaxation after nanosecond T-jump. In this work we observed folding of this protein after dilution of a high denaturant in an ultrarapid microfluidic mixer at temperatures far below the thermal midpoint. The observations of total intensity and spectral shift of tryptophan fluorescence yielded distinctly different kinetics and activation energies. These results may be explained as diffusion on a low-barrier, one-dimensional, free-energy surface, with different probes having different sensitivities along the reaction coordinate. Additionally, we observed an extremely fast phase within the mixing time that was not observed by T-jump, suggesting that the ensemble of unfolded states populated at high denaturant is distinct from those accessible at high temperature. | lld:pubmed |
| pubmed-article:19751683 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19751683 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19751683 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19751683 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19751683 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19751683 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19751683 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19751683 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:19751683 | pubmed:issn | 1542-0086 | lld:pubmed |
| pubmed-article:19751683 | pubmed:author | pubmed-author:LapidusLisa... | lld:pubmed |
| pubmed-article:19751683 | pubmed:author | pubmed-author:BakajinOlgica... | lld:pubmed |
| pubmed-article:19751683 | pubmed:author | pubmed-author:NaganathanAth... | lld:pubmed |
| pubmed-article:19751683 | pubmed:author | pubmed-author:WaldauerSteve... | lld:pubmed |
| pubmed-article:19751683 | pubmed:author | pubmed-author:DeCampStephen... | lld:pubmed |
| pubmed-article:19751683 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19751683 | pubmed:day | 16 | lld:pubmed |
| pubmed-article:19751683 | pubmed:volume | 97 | lld:pubmed |
| pubmed-article:19751683 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19751683 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19751683 | pubmed:pagination | 1772-7 | lld:pubmed |
| pubmed-article:19751683 | pubmed:dateRevised | 2010-9-17 | lld:pubmed |
| pubmed-article:19751683 | pubmed:meshHeading | pubmed-meshheading:19751683... | lld:pubmed |
| pubmed-article:19751683 | pubmed:meshHeading | pubmed-meshheading:19751683... | lld:pubmed |
| pubmed-article:19751683 | pubmed:meshHeading | pubmed-meshheading:19751683... | lld:pubmed |
| pubmed-article:19751683 | pubmed:meshHeading | pubmed-meshheading:19751683... | lld:pubmed |
| pubmed-article:19751683 | pubmed:meshHeading | pubmed-meshheading:19751683... | lld:pubmed |
| pubmed-article:19751683 | pubmed:meshHeading | pubmed-meshheading:19751683... | lld:pubmed |
| pubmed-article:19751683 | pubmed:meshHeading | pubmed-meshheading:19751683... | lld:pubmed |
| pubmed-article:19751683 | pubmed:meshHeading | pubmed-meshheading:19751683... | lld:pubmed |
| pubmed-article:19751683 | pubmed:meshHeading | pubmed-meshheading:19751683... | lld:pubmed |
| pubmed-article:19751683 | pubmed:meshHeading | pubmed-meshheading:19751683... | lld:pubmed |
| pubmed-article:19751683 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:19751683 | pubmed:articleTitle | Direct observation of downhill folding of lambda-repressor in a microfluidic mixer. | lld:pubmed |
| pubmed-article:19751683 | pubmed:affiliation | Department of Physics and Astronomy, Michigan State University, East Lansing, Michigan, USA. | lld:pubmed |
| pubmed-article:19751683 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19751683 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:19751683 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:19751683 | lld:pubmed |
