| pubmed-article:1974339 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1974339 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:1974339 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:1974339 | lifeskim:mentions | umls-concept:C0010097 | lld:lifeskim |
| pubmed-article:1974339 | lifeskim:mentions | umls-concept:C0162512 | lld:lifeskim |
| pubmed-article:1974339 | lifeskim:mentions | umls-concept:C0005516 | lld:lifeskim |
| pubmed-article:1974339 | lifeskim:mentions | umls-concept:C0282151 | lld:lifeskim |
| pubmed-article:1974339 | lifeskim:mentions | umls-concept:C0175631 | lld:lifeskim |
| pubmed-article:1974339 | lifeskim:mentions | umls-concept:C0011307 | lld:lifeskim |
| pubmed-article:1974339 | lifeskim:mentions | umls-concept:C2827662 | lld:lifeskim |
| pubmed-article:1974339 | lifeskim:mentions | umls-concept:C0058123 | lld:lifeskim |
| pubmed-article:1974339 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:1974339 | pubmed:dateCreated | 1990-9-13 | lld:pubmed |
| pubmed-article:1974339 | pubmed:abstractText | [3H]Dihydrotetrabenazine ([3H]TBZOH), a derivative of the monoamine depleting agent, tetrabenazine, has been shown to bind to the vesicular monoamine transporter. We studied the effect of unilateral nigral lesion with 6-hydroxydopamine on [3H]TBZOH binding in the striatum by means of quantitative autoradiography. Topographical analysis of striatal [3H]TBZOH binding showed in control rats a pattern similar to the known distribution of dopaminergic innervation, and allowed to visualize dopaminergic denervation in lesioned rats. A good correlation was found between striatal [3H]TBZOH binding levels and tyrosine hydroxylase activities in similar areas on adjacent slices following 6-OHDA lesions with varying severity. These data reveal that autoradiography of [3H]TBZOH binding is a good index for the visualization and quantitation of dopaminergic nerve terminals integrity in the striatum. | lld:pubmed |
| pubmed-article:1974339 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1974339 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1974339 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1974339 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1974339 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1974339 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1974339 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1974339 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1974339 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1974339 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1974339 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:1974339 | pubmed:issn | 0304-3940 | lld:pubmed |
| pubmed-article:1974339 | pubmed:author | pubmed-author:SchermanDD | lld:pubmed |
| pubmed-article:1974339 | pubmed:author | pubmed-author:MasuiSS | lld:pubmed |
| pubmed-article:1974339 | pubmed:author | pubmed-author:RostèneWW | lld:pubmed |
| pubmed-article:1974339 | pubmed:author | pubmed-author:PélapratDD | lld:pubmed |
| pubmed-article:1974339 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1974339 | pubmed:day | 22 | lld:pubmed |
| pubmed-article:1974339 | pubmed:volume | 114 | lld:pubmed |
| pubmed-article:1974339 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1974339 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1974339 | pubmed:pagination | 45-50 | lld:pubmed |
| pubmed-article:1974339 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:1974339 | pubmed:meshHeading | pubmed-meshheading:1974339-... | lld:pubmed |
| pubmed-article:1974339 | pubmed:meshHeading | pubmed-meshheading:1974339-... | lld:pubmed |
| pubmed-article:1974339 | pubmed:meshHeading | pubmed-meshheading:1974339-... | lld:pubmed |
| pubmed-article:1974339 | pubmed:meshHeading | pubmed-meshheading:1974339-... | lld:pubmed |
| pubmed-article:1974339 | pubmed:meshHeading | pubmed-meshheading:1974339-... | lld:pubmed |
| pubmed-article:1974339 | pubmed:meshHeading | pubmed-meshheading:1974339-... | lld:pubmed |
| pubmed-article:1974339 | pubmed:meshHeading | pubmed-meshheading:1974339-... | lld:pubmed |
| pubmed-article:1974339 | pubmed:meshHeading | pubmed-meshheading:1974339-... | lld:pubmed |
| pubmed-article:1974339 | pubmed:meshHeading | pubmed-meshheading:1974339-... | lld:pubmed |
| pubmed-article:1974339 | pubmed:meshHeading | pubmed-meshheading:1974339-... | lld:pubmed |
| pubmed-article:1974339 | pubmed:meshHeading | pubmed-meshheading:1974339-... | lld:pubmed |
| pubmed-article:1974339 | pubmed:meshHeading | pubmed-meshheading:1974339-... | lld:pubmed |
| pubmed-article:1974339 | pubmed:meshHeading | pubmed-meshheading:1974339-... | lld:pubmed |
| pubmed-article:1974339 | pubmed:meshHeading | pubmed-meshheading:1974339-... | lld:pubmed |
| pubmed-article:1974339 | pubmed:meshHeading | pubmed-meshheading:1974339-... | lld:pubmed |
| pubmed-article:1974339 | pubmed:meshHeading | pubmed-meshheading:1974339-... | lld:pubmed |
| pubmed-article:1974339 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:1974339 | pubmed:articleTitle | [3H]Dihydrotetrabenazine, a new marker for the visualization of dopaminergic denervation in the rat striatum. | lld:pubmed |
| pubmed-article:1974339 | pubmed:affiliation | INSERM U.55, Hôpital Saint-Antoine, Paris, France. | lld:pubmed |
| pubmed-article:1974339 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1974339 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1974339 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1974339 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1974339 | lld:pubmed |
