Activation of phosphatidylinositol 3'-kinase pathway is implicated in the pathogenesis of mantle cell lymphoma (MCL). The genetic change in phosphatidylinositol 3'-kinase catalytic subunit alpha (PIK3CA) in MCL has not been identified.
Second Department of Internal Medicine, Propaedeutic, University of Athens, University General Hospital "Attikon", Haidari, Athens, Greece. diamando.psyrri@yale.edu
