| pubmed-article:1971203 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1971203 | lifeskim:mentions | umls-concept:C0012655 | lld:lifeskim |
| pubmed-article:1971203 | lifeskim:mentions | umls-concept:C1704321 | lld:lifeskim |
| pubmed-article:1971203 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:1971203 | lifeskim:mentions | umls-concept:C0019780 | lld:lifeskim |
| pubmed-article:1971203 | lifeskim:mentions | umls-concept:C0679058 | lld:lifeskim |
| pubmed-article:1971203 | lifeskim:mentions | umls-concept:C1521761 | lld:lifeskim |
| pubmed-article:1971203 | lifeskim:mentions | umls-concept:C0205164 | lld:lifeskim |
| pubmed-article:1971203 | lifeskim:mentions | umls-concept:C1547699 | lld:lifeskim |
| pubmed-article:1971203 | lifeskim:mentions | umls-concept:C2700640 | lld:lifeskim |
| pubmed-article:1971203 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:1971203 | pubmed:dateCreated | 1990-6-25 | lld:pubmed |
| pubmed-article:1971203 | pubmed:abstractText | 1. We have investigated the frequencies of the major histocompatibility complex class II alleles by restriction fragment length polymorphism analysis, using DR, DQ and DP complementary DNA probes, in 40 Caucasoid steroid-sensitive nephrotic children. 2. A significant association with HLA-DR7 was demonstrated (P = 2 x 10(-5); aetiological fraction 0.6). The DQB1 gene of HLA-DQw2 was present in 83% of our patients (P = 2 x 10(-4); aetiological fraction 0.7). We present evidence that it contributes a second susceptibility allele. 3. A weak association between the uncommon HLA-DP-Cp63 allele and the disease was also observed. 4. Our data suggest that the immune events in steroid-sensitive nephrotic syndrome are defined by a particular immunogenetic background involving the beta-chain genes of HLA-DR7 and HLA-DQw2. | lld:pubmed |
| pubmed-article:1971203 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1971203 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1971203 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1971203 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1971203 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1971203 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1971203 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1971203 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1971203 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1971203 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:1971203 | pubmed:issn | 0143-5221 | lld:pubmed |
| pubmed-article:1971203 | pubmed:author | pubmed-author:ClarkA GAG | lld:pubmed |
| pubmed-article:1971203 | pubmed:author | pubmed-author:VaughanR WRW | lld:pubmed |
| pubmed-article:1971203 | pubmed:author | pubmed-author:WilliamsD GDG | lld:pubmed |
| pubmed-article:1971203 | pubmed:author | pubmed-author:WelshK IKI | lld:pubmed |
| pubmed-article:1971203 | pubmed:author | pubmed-author:ChantlerCC | lld:pubmed |
| pubmed-article:1971203 | pubmed:author | pubmed-author:StephensH AHA | lld:pubmed |
| pubmed-article:1971203 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1971203 | pubmed:volume | 78 | lld:pubmed |
| pubmed-article:1971203 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1971203 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1971203 | pubmed:pagination | 391-7 | lld:pubmed |
| pubmed-article:1971203 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
| pubmed-article:1971203 | pubmed:meshHeading | pubmed-meshheading:1971203-... | lld:pubmed |
| pubmed-article:1971203 | pubmed:meshHeading | pubmed-meshheading:1971203-... | lld:pubmed |
| pubmed-article:1971203 | pubmed:meshHeading | pubmed-meshheading:1971203-... | lld:pubmed |
| pubmed-article:1971203 | pubmed:meshHeading | pubmed-meshheading:1971203-... | lld:pubmed |
| pubmed-article:1971203 | pubmed:meshHeading | pubmed-meshheading:1971203-... | lld:pubmed |
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| pubmed-article:1971203 | pubmed:meshHeading | pubmed-meshheading:1971203-... | lld:pubmed |
| pubmed-article:1971203 | pubmed:meshHeading | pubmed-meshheading:1971203-... | lld:pubmed |
| pubmed-article:1971203 | pubmed:meshHeading | pubmed-meshheading:1971203-... | lld:pubmed |
| pubmed-article:1971203 | pubmed:meshHeading | pubmed-meshheading:1971203-... | lld:pubmed |
| pubmed-article:1971203 | pubmed:meshHeading | pubmed-meshheading:1971203-... | lld:pubmed |
| pubmed-article:1971203 | pubmed:meshHeading | pubmed-meshheading:1971203-... | lld:pubmed |
| pubmed-article:1971203 | pubmed:meshHeading | pubmed-meshheading:1971203-... | lld:pubmed |
| pubmed-article:1971203 | pubmed:meshHeading | pubmed-meshheading:1971203-... | lld:pubmed |
| pubmed-article:1971203 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:1971203 | pubmed:articleTitle | Genes encoding the beta-chains of HLA-DR7 and HLA-DQw2 define major susceptibility determinants for idiopathic nephrotic syndrome. | lld:pubmed |
| pubmed-article:1971203 | pubmed:affiliation | Evelina Children's Department, United Medical School, St Thomas Hospital, London. | lld:pubmed |
| pubmed-article:1971203 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1971203 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1971203 | lld:pubmed |
