Affinity maturation by targeted diversification of the CDR-H2 loop of a monoclonal Fab derived from a synthetic naïve human antibody library and directed against the internal trimeric coiled-coil of gp41 yields a set of Fabs with improved HIV-1 neutralization potency and breadth.
Source:http://linkedlifedata.com/resource/pubmed/id/19695655
Virology
2009
Oct
10
393
1
112-9
