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pubmed-article:19694825pubmed:abstractTextThe aim was to assess the value of GCC in distinguishing primary ovarian mucinous neoplasms from metastatic mucinous adenocarcinomas with ovarian involvement. Guanylyl cyclase C (GCC) is a brush border membrane receptor for the endogenous peptides guanylin and uroguanylin, and the homologous diarrhoeagenic bacterial heat-stable enterotoxins that is selectively expressed by epithelial cells from the duodenum to the rectum, but not by normal epithelia of the stomach or oesophagus, or normal extramucosal cells in humans.lld:pubmed
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pubmed-article:19694825pubmed:articleTitleGuanylyl cyclase C is a specific marker for differentiating primary and metastatic ovarian mucinous neoplasms.lld:pubmed
pubmed-article:19694825pubmed:affiliationDepartment of Pathology, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA.lld:pubmed
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