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pubmed-article:19673746pubmed:abstractTextAlcohol dependence is extremely common in patients with bipolar disorder and is associated with unfavorable outcomes including treatment nonadherence, violence, increased hospitalization, and decreased quality of life. While naltrexone is a standard treatment for alcohol dependence, no controlled trials have examined its use in patients with co-morbid bipolar disorder and alcohol dependence. In this pilot study, the efficacy of naltrexone in reducing alcohol use and on mood symptoms was assessed in bipolar disorder and alcohol dependence.lld:pubmed
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pubmed-article:19673746pubmed:articleTitleA randomized, double-blind, placebo-controlled pilot study of naltrexone in outpatients with bipolar disorder and alcohol dependence.lld:pubmed
pubmed-article:19673746pubmed:affiliationDepartment of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, TX, USA. sherwood.brown@utsouthwestern.edulld:pubmed
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