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pubmed-article:19659868pubmed:abstractTextPretibial epidermolysis bullosa (PEB) is an extremely rare subtype of dominant dystrophic epidermolysis bullosa (DDEB), in which recurrent blistering with scarring predominantly involves the pretibial skin. Nail dystrophy, albopapuloid lesions, and hypertrophic scars may also occur. In PEB, immunohistochemical and electron microscopic studies demonstrate the complete or partial loss of the anchoring fibril (AF) in the basement membrane zone, suggesting disturbed synthesis or excessive degradation of collagen VII, the main component of AF. Interestingly, we report a case of PEB with unusual results of joint loss of types IV and VII collagen.lld:pubmed
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pubmed-article:19659868pubmed:authorpubmed-author:KimSeong...lld:pubmed
pubmed-article:19659868pubmed:authorpubmed-author:ParkKunKlld:pubmed
pubmed-article:19659868pubmed:authorpubmed-author:LeeHong-sunHSlld:pubmed
pubmed-article:19659868pubmed:authorpubmed-author:SonSook-jaSJlld:pubmed
pubmed-article:19659868pubmed:authorpubmed-author:SongKye-yongK...lld:pubmed
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pubmed-article:19659868pubmed:year2009lld:pubmed
pubmed-article:19659868pubmed:articleTitlePretibial epidermolysis bullosa: is this case a new subtype with loss of types IV and VII collagen?lld:pubmed
pubmed-article:19659868pubmed:affiliationDepartment of Dermatology, College of Medicine, Eulji University, Seoul, South Korea.lld:pubmed
pubmed-article:19659868pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:19659868pubmed:publicationTypeCase Reportslld:pubmed