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pubmed-article:19652703pubmed:abstractTextDengue fever (DF) is an emerging infectious disease in the tropics and subtropics. Determinants of DF epidemiology and factors involved in severe cases-dengue haemorrhagic fever (DHF) and dengue shock syndrome (DSS)-remain imperfectly characterized. Since 2000, serotype 1 (DENV-1) has predominated in the South Pacific. The aim of this study was (i) to determine the origin and (ii) to study the evolutionary relationships of DENV-1 viruses that have circulated in French Polynesia (FP) from the severe 2001 outbreak to the recent 2006 epidemic, and (iii) to analyse the viral intra-host genetic diversity according to clinical presentation.lld:pubmed
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pubmed-article:19652703pubmed:authorpubmed-author:RocheClaudine...lld:pubmed
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pubmed-article:19652703pubmed:dateRevised2010-9-27lld:pubmed
pubmed-article:19652703pubmed:year2009lld:pubmed
pubmed-article:19652703pubmed:articleTitleDengue 1 diversity and microevolution, French Polynesia 2001-2006: connection with epidemiology and clinics.lld:pubmed
pubmed-article:19652703pubmed:affiliationUMR190, Emergence des Pathologies Virales, Université de la Méditerranée and Institut de Recherche pour le Développement, Marseille, France.lld:pubmed
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