Effects of tamsulosin on bladder blood flow and bladder function in rats with bladder outlet obstruction.

Source:http://linkedlifedata.com/resource/pubmed/id/19647304

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Authors

Suzuki M, Uemura H, Kurita T, Sato S, Matsumoto S, Sasamata M, Hanai T, Okutsu H, Fujiyasu N, Ohtake A, Noguchi Y

Affiliation

Applied Pharmacology Research Laboratories, Astellas Pharma Inc, Miyukigaoka, Tsukuba-shi, Ibaraki, Japan.

Abstract

To investigate the mechanism underlying the ameliorating effect of tamsulosin, an alpha(1)-adrenoceptor antagonist, on storage symptoms associated with benign prostatic hyperplasia, the effects of tamsulosin on bladder blood flow (BBF) and bladder function was evaluated in rats with bladder outlet obstruction (BOO).

PMID
19647304