| pubmed-article:19639997 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19639997 | lifeskim:mentions | umls-concept:C0001992 | lld:lifeskim |
| pubmed-article:19639997 | lifeskim:mentions | umls-concept:C0443286 | lld:lifeskim |
| pubmed-article:19639997 | lifeskim:mentions | umls-concept:C1704259 | lld:lifeskim |
| pubmed-article:19639997 | lifeskim:mentions | umls-concept:C0007382 | lld:lifeskim |
| pubmed-article:19639997 | lifeskim:mentions | umls-concept:C1705987 | lld:lifeskim |
| pubmed-article:19639997 | lifeskim:mentions | umls-concept:C1705938 | lld:lifeskim |
| pubmed-article:19639997 | lifeskim:mentions | umls-concept:C1527178 | lld:lifeskim |
| pubmed-article:19639997 | pubmed:issue | 33 | lld:pubmed |
| pubmed-article:19639997 | pubmed:dateCreated | 2009-9-2 | lld:pubmed |
| pubmed-article:19639997 | pubmed:abstractText | The intramolecular alpha-arylation of aldehydes has been accomplished using singly occupied molecular orbital (SOMO) catalysis. Selective oxidation of chiral enamines (formed by the condensation of an aldehyde and a secondary amine catalyst) leads to the formation of a 3pi-electron radical species. These chiral SOMO-activated radical cations undergo enantioselective reaction with an array of pendent electron-rich aromatics and heterocycles thus efficiently providing cyclic alpha-aryl aldehyde products (10 examples: > or = 70% yield and > or = 90% ee). In accordance with our radical mechanism, when there is a choice between arylation at the ortho or para position of anisole substrates, we find that arylation proceeds selectively at the ortho position. | lld:pubmed |
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| pubmed-article:19639997 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19639997 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19639997 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:19639997 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19639997 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:19639997 | pubmed:issn | 1520-5126 | lld:pubmed |
| pubmed-article:19639997 | pubmed:author | pubmed-author:MacMillanDavi... | lld:pubmed |
| pubmed-article:19639997 | pubmed:author | pubmed-author:ConradJay CJC | lld:pubmed |
| pubmed-article:19639997 | pubmed:author | pubmed-author:KongJongrockJ | lld:pubmed |
| pubmed-article:19639997 | pubmed:author | pubmed-author:LafortezaBria... | lld:pubmed |
| pubmed-article:19639997 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19639997 | pubmed:day | 26 | lld:pubmed |
| pubmed-article:19639997 | pubmed:volume | 131 | lld:pubmed |
| pubmed-article:19639997 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19639997 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19639997 | pubmed:pagination | 11640-1 | lld:pubmed |
| pubmed-article:19639997 | pubmed:dateRevised | 2010-9-27 | lld:pubmed |
| pubmed-article:19639997 | pubmed:meshHeading | pubmed-meshheading:19639997... | lld:pubmed |
| pubmed-article:19639997 | pubmed:meshHeading | pubmed-meshheading:19639997... | lld:pubmed |
| pubmed-article:19639997 | pubmed:meshHeading | pubmed-meshheading:19639997... | lld:pubmed |
| pubmed-article:19639997 | pubmed:meshHeading | pubmed-meshheading:19639997... | lld:pubmed |
| pubmed-article:19639997 | pubmed:meshHeading | pubmed-meshheading:19639997... | lld:pubmed |
| pubmed-article:19639997 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:19639997 | pubmed:articleTitle | Enantioselective alpha-arylation of aldehydes via organo-SOMO catalysis. An ortho-selective arylation reaction based on an open-shell pathway. | lld:pubmed |
| pubmed-article:19639997 | pubmed:affiliation | Merck Center for Catalysis at Princeton University, Princeton, New Jersey 08544, USA. | lld:pubmed |
| pubmed-article:19639997 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19639997 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:19639997 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
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