| pubmed-article:1963917 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1963917 | lifeskim:mentions | umls-concept:C0019196 | lld:lifeskim |
| pubmed-article:1963917 | lifeskim:mentions | umls-concept:C0042720 | lld:lifeskim |
| pubmed-article:1963917 | lifeskim:mentions | umls-concept:C1519249 | lld:lifeskim |
| pubmed-article:1963917 | lifeskim:mentions | umls-concept:C1880371 | lld:lifeskim |
| pubmed-article:1963917 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:1963917 | pubmed:dateCreated | 1991-4-19 | lld:pubmed |
| pubmed-article:1963917 | pubmed:abstractText | The nucleotide sequences of cDNAs (275 base-pairs) in the non-structural protein 5 regions of Japanese isolates of hepatitis C virus (HCV-J) from the plasma of 11 patients with non-A, non-B hepatitis and the livers of five patients with hepatocellular carcinoma were analyzed. Approximately 14 to 17% of nucleotide sequences of the HCV-Js examined differed from that of the original isolate in the United States (HCV-US). Furthermore, 2.5 to 11% sequence diversity was found among the HCV-Js. The nucleotide sequences of the HCV-Js showed characteristic common differences from that of HCV-US, although they also showed some random substitutions. Plural HCV-J genomes were found in two of the cDNAs derived from liver specimens, and a deletion of 102 nucleotides was found in the cDNA derived from one plasma specimen. These results suggest that HCV-J is a strain different from the HCV-US and that mutation of the viral genome occurs at as high a frequency as in that of the human immunodeficiency virus. | lld:pubmed |
| pubmed-article:1963917 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1963917 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1963917 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1963917 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1963917 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1963917 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1963917 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:1963917 | pubmed:issn | 0735-1313 | lld:pubmed |
| pubmed-article:1963917 | pubmed:author | pubmed-author:KatoNN | lld:pubmed |
| pubmed-article:1963917 | pubmed:author | pubmed-author:ShimotohnoKK | lld:pubmed |
| pubmed-article:1963917 | pubmed:author | pubmed-author:NakagawaMM | lld:pubmed |
| pubmed-article:1963917 | pubmed:author | pubmed-author:HijikataMM | lld:pubmed |
| pubmed-article:1963917 | pubmed:author | pubmed-author:OotsuyamaYY | lld:pubmed |
| pubmed-article:1963917 | pubmed:author | pubmed-author:OhkoshiSS | lld:pubmed |
| pubmed-article:1963917 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1963917 | pubmed:volume | 7 | lld:pubmed |
| pubmed-article:1963917 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1963917 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1963917 | pubmed:pagination | 495-501 | lld:pubmed |
| pubmed-article:1963917 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:1963917 | pubmed:meshHeading | pubmed-meshheading:1963917-... | lld:pubmed |
| pubmed-article:1963917 | pubmed:meshHeading | pubmed-meshheading:1963917-... | lld:pubmed |
| pubmed-article:1963917 | pubmed:meshHeading | pubmed-meshheading:1963917-... | lld:pubmed |
| pubmed-article:1963917 | pubmed:meshHeading | pubmed-meshheading:1963917-... | lld:pubmed |
| pubmed-article:1963917 | pubmed:meshHeading | pubmed-meshheading:1963917-... | lld:pubmed |
| pubmed-article:1963917 | pubmed:meshHeading | pubmed-meshheading:1963917-... | lld:pubmed |
| pubmed-article:1963917 | pubmed:meshHeading | pubmed-meshheading:1963917-... | lld:pubmed |
| pubmed-article:1963917 | pubmed:meshHeading | pubmed-meshheading:1963917-... | lld:pubmed |
| pubmed-article:1963917 | pubmed:meshHeading | pubmed-meshheading:1963917-... | lld:pubmed |
| pubmed-article:1963917 | pubmed:meshHeading | pubmed-meshheading:1963917-... | lld:pubmed |
| pubmed-article:1963917 | pubmed:meshHeading | pubmed-meshheading:1963917-... | lld:pubmed |
| pubmed-article:1963917 | pubmed:meshHeading | pubmed-meshheading:1963917-... | lld:pubmed |
| pubmed-article:1963917 | pubmed:meshHeading | pubmed-meshheading:1963917-... | lld:pubmed |
| pubmed-article:1963917 | pubmed:meshHeading | pubmed-meshheading:1963917-... | lld:pubmed |
| pubmed-article:1963917 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:1963917 | pubmed:articleTitle | Sequence diversity of hepatitis C viral genomes. | lld:pubmed |
| pubmed-article:1963917 | pubmed:affiliation | Virology Division, National Cancer Center Research Institute, Tokyo, Japan. | lld:pubmed |
| pubmed-article:1963917 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1963917 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1963917 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1963917 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1963917 | lld:pubmed |
