| pubmed-article:19624506 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19624506 | lifeskim:mentions | umls-concept:C0025663 | lld:lifeskim |
| pubmed-article:19624506 | lifeskim:mentions | umls-concept:C1519249 | lld:lifeskim |
| pubmed-article:19624506 | lifeskim:mentions | umls-concept:C0037633 | lld:lifeskim |
| pubmed-article:19624506 | lifeskim:mentions | umls-concept:C0018570 | lld:lifeskim |
| pubmed-article:19624506 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:19624506 | lifeskim:mentions | umls-concept:C1382100 | lld:lifeskim |
| pubmed-article:19624506 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:19624506 | pubmed:dateCreated | 2010-4-19 | lld:pubmed |
| pubmed-article:19624506 | pubmed:abstractText | The use of alcohol-based hand rubs serves to reduce hospital-acquired infections. Many products of this type are now on offer and it is essential to know how to rank their efficacy. A sequence of tests is proposed here to compare any given new alcohol-based solution against the reference solution (60% 2-isopropyl-alcohol) with 30 s of contact time: (i) in vitro (with pig skin as carrier) testing of >30 species of microorganism; (ii) in vitro assessment of residual efficacy (after 30 min of drying); (iii) in vivo study of transient microbiota (modification of the EN 1500 standard procedure) using four ATCC strains; (iv) in vivo study of resident hand microbiota. After performing the in vitro evaluation of seven alcohol-based hand rubs, the two most efficacious (chlorhexidine-quac-alcohol and mecetronium- alcohol) were chosen and studied, comparatively with the reference solution (60% isopropyl alcohol), in vitro (for chemical sustainability on the skin) and in vivo (against transient and resident microbiota). Chlorhexidine-quac-alcohol proved to be significantly superior to mecetronium-alcohol or the reference solution in all tests, except against resident microbiota for which the improvement was not statistically significant. | lld:pubmed |
| pubmed-article:19624506 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19624506 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19624506 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19624506 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19624506 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19624506 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19624506 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19624506 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19624506 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19624506 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19624506 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19624506 | pubmed:month | May | lld:pubmed |
| pubmed-article:19624506 | pubmed:issn | 1469-0691 | lld:pubmed |
| pubmed-article:19624506 | pubmed:author | pubmed-author:VizcainoM JMJ | lld:pubmed |
| pubmed-article:19624506 | pubmed:author | pubmed-author:HerruzoRR | lld:pubmed |
| pubmed-article:19624506 | pubmed:author | pubmed-author:HerruzoII | lld:pubmed |
| pubmed-article:19624506 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19624506 | pubmed:volume | 16 | lld:pubmed |
| pubmed-article:19624506 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19624506 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19624506 | pubmed:pagination | 518-23 | lld:pubmed |
| pubmed-article:19624506 | pubmed:meshHeading | pubmed-meshheading:19624506... | lld:pubmed |
| pubmed-article:19624506 | pubmed:meshHeading | pubmed-meshheading:19624506... | lld:pubmed |
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| pubmed-article:19624506 | pubmed:meshHeading | pubmed-meshheading:19624506... | lld:pubmed |
| pubmed-article:19624506 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:19624506 | pubmed:articleTitle | In vitro-in vivo sequence studies as a method of selecting the most efficacious alcohol-based solution for hygienic hand disinfection. | lld:pubmed |
| pubmed-article:19624506 | pubmed:affiliation | Department of Preventive Medicine, Autonomous University of Madrid, Spain. rafael.herruzo@uam.es <rafael.herruzo@uam.es> | lld:pubmed |
| pubmed-article:19624506 | pubmed:publicationType | Journal Article | lld:pubmed |
