| pubmed-article:19623759 | pubmed:abstractText | Variants in numerous genes are thought to affect the success or failure of cancer chemotherapy. Interindividual variability can result from genes involved in drug metabolism and transport, drug targets (receptors, enzymes, etc), and proteins relevant to cell survival (e.g., cell cycle, DNA repair, and apoptosis). The purpose of the current study is to establish a flexible, cost effective,high-throughput genotyping platform for candidate genes involved in chemo resistance and -sensitivity, and treatment outcomes. | lld:pubmed |
| pubmed-article:19623759 | pubmed:affiliation | Program in Pharmacogenomics, Department of Pharmacology, Comprehensive Cancer Center, College of Medicine and Public Health,The Ohio State University, 5072 Graves Hall, 333 West 10th Avenue, Columbus, OH 43210-1239, USA. dai.15@osu.edu | lld:pubmed |
