| pubmed-article:19622355 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19622355 | lifeskim:mentions | umls-concept:C0036025 | lld:lifeskim |
| pubmed-article:19622355 | lifeskim:mentions | umls-concept:C0040711 | lld:lifeskim |
| pubmed-article:19622355 | lifeskim:mentions | umls-concept:C0030016 | lld:lifeskim |
| pubmed-article:19622355 | lifeskim:mentions | umls-concept:C0301630 | lld:lifeskim |
| pubmed-article:19622355 | lifeskim:mentions | umls-concept:C1879547 | lld:lifeskim |
| pubmed-article:19622355 | pubmed:issue | 17 | lld:pubmed |
| pubmed-article:19622355 | pubmed:dateCreated | 2009-9-1 | lld:pubmed |
| pubmed-article:19622355 | pubmed:abstractText | Previously we reported that in vitro translation activity in extracts of Saccharomyces cerevisiae was stimulated by dithiothreitol (DTT) and further increased by the addition of thioredoxin (TRX1) [Choi, S.K. (2007) Thioredoxin-mediated regulation of protein synthesis by redox in Saccharomyces cerevisiae. Kor. J. Microbiol. Biotechnol. 35, 36-40]. To identify the pathway affecting translation, we cloned and purified thioredoxin reductase 1 (TRR1), thioredoxin reductase 2 (TRR2), glutaredoxin 1 (GRX1) and glutaredoxin reductase 1 (GLR1) as fusion proteins. Thioredoxin-mediated activation of translation was more effectively stimulated by NADPH or NADH than by DTT. Moreover, addition of TRR1 led to a further increase of translation in the presence of thioredoxin plus NADPH. These findings indicate that redox control via the thioredoxin-thioredoxin reductase system plays an important role in the regulation of translation. | lld:pubmed |
| pubmed-article:19622355 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19622355 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19622355 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19622355 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19622355 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19622355 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19622355 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19622355 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19622355 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19622355 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19622355 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19622355 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19622355 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:19622355 | pubmed:issn | 1873-3468 | lld:pubmed |
| pubmed-article:19622355 | pubmed:author | pubmed-author:KimYoung-BumY... | lld:pubmed |
| pubmed-article:19622355 | pubmed:author | pubmed-author:ChoiSang KiSK | lld:pubmed |
| pubmed-article:19622355 | pubmed:author | pubmed-author:JunKyung OkKO | lld:pubmed |
| pubmed-article:19622355 | pubmed:author | pubmed-author:SongChin-HeeC... | lld:pubmed |
| pubmed-article:19622355 | pubmed:author | pubmed-author:AnJinseokJ | lld:pubmed |
| pubmed-article:19622355 | pubmed:author | pubmed-author:OhJae HyeunJH | lld:pubmed |
| pubmed-article:19622355 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19622355 | pubmed:day | 3 | lld:pubmed |
| pubmed-article:19622355 | pubmed:volume | 583 | lld:pubmed |
| pubmed-article:19622355 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19622355 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19622355 | pubmed:pagination | 2804-10 | lld:pubmed |
| pubmed-article:19622355 | pubmed:meshHeading | pubmed-meshheading:19622355... | lld:pubmed |
| pubmed-article:19622355 | pubmed:meshHeading | pubmed-meshheading:19622355... | lld:pubmed |
| pubmed-article:19622355 | pubmed:meshHeading | pubmed-meshheading:19622355... | lld:pubmed |
| pubmed-article:19622355 | pubmed:meshHeading | pubmed-meshheading:19622355... | lld:pubmed |
| pubmed-article:19622355 | pubmed:meshHeading | pubmed-meshheading:19622355... | lld:pubmed |
| pubmed-article:19622355 | pubmed:meshHeading | pubmed-meshheading:19622355... | lld:pubmed |
| pubmed-article:19622355 | pubmed:meshHeading | pubmed-meshheading:19622355... | lld:pubmed |
| pubmed-article:19622355 | pubmed:meshHeading | pubmed-meshheading:19622355... | lld:pubmed |
| pubmed-article:19622355 | pubmed:meshHeading | pubmed-meshheading:19622355... | lld:pubmed |
| pubmed-article:19622355 | pubmed:meshHeading | pubmed-meshheading:19622355... | lld:pubmed |
| pubmed-article:19622355 | pubmed:meshHeading | pubmed-meshheading:19622355... | lld:pubmed |
| pubmed-article:19622355 | pubmed:meshHeading | pubmed-meshheading:19622355... | lld:pubmed |
| pubmed-article:19622355 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:19622355 | pubmed:articleTitle | Activation of translation via reduction by thioredoxin-thioredoxin reductase in Saccharomyces cerevisiae. | lld:pubmed |
| pubmed-article:19622355 | pubmed:affiliation | Department of Biological Sciences, College of Life Industry and Science, Sunchon National University, Jeonnam, Republic of Korea. | lld:pubmed |
| pubmed-article:19622355 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19622355 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:19622355 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:19622355 | lld:entrezgene |
