The P1N-isopropyl motif bearing hydroxyethylene dipeptide isostere analogues of aliskiren are in vitro potent inhibitors of the human aspartyl protease renin.

Source:http://linkedlifedata.com/resource/pubmed/id/19615901

Bioorg. Med. Chem. Lett. 2009 Aug 15 19 16 4863-7

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PMID
19615901