| pubmed-article:19601999 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19601999 | lifeskim:mentions | umls-concept:C0229671 | lld:lifeskim |
| pubmed-article:19601999 | lifeskim:mentions | umls-concept:C0069676 | lld:lifeskim |
| pubmed-article:19601999 | lifeskim:mentions | umls-concept:C0040690 | lld:lifeskim |
| pubmed-article:19601999 | lifeskim:mentions | umls-concept:C0332281 | lld:lifeskim |
| pubmed-article:19601999 | lifeskim:mentions | umls-concept:C0032529 | lld:lifeskim |
| pubmed-article:19601999 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:19601999 | pubmed:dateCreated | 2009-7-15 | lld:pubmed |
| pubmed-article:19601999 | pubmed:abstractText | Osteopontin (OPN) is a secreted glycoprotein demonstrated to play an important role in inflammation. Transforming growth factor beta and a related signalling pathway have been implicated in control of OPN secretion. We examined the relationship between transforming growth factor beta receptor-1 and -2 (TGFBR1 and 2) single nucleotide polymorphisms (SNP) and serum OPN in 296 men from the Health in Men Study. Serum concentrations of OPN and 58 SNPs for TGFBR1 and 2 were assessed. One SNP in TGFBR2 was associated with serum OPN (TGFBR2 g.20690C>T, SNP ID rs4522809, P = 0.0007) after adjusting for multiple testing. This study suggests that polymorphism in TGFBR2 are associated with altered secretion of OPN, supporting a role for transforming growth factor beta in OPN production. | lld:pubmed |
| pubmed-article:19601999 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19601999 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19601999 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19601999 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19601999 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19601999 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19601999 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19601999 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19601999 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19601999 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19601999 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:19601999 | pubmed:issn | 1744-313X | lld:pubmed |
| pubmed-article:19601999 | pubmed:author | pubmed-author:NormanP EPE | lld:pubmed |
| pubmed-article:19601999 | pubmed:author | pubmed-author:ClancyPP | lld:pubmed |
| pubmed-article:19601999 | pubmed:author | pubmed-author:GolledgeJJ | lld:pubmed |
| pubmed-article:19601999 | pubmed:author | pubmed-author:BirosEE | lld:pubmed |
| pubmed-article:19601999 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19601999 | pubmed:volume | 36 | lld:pubmed |
| pubmed-article:19601999 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19601999 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19601999 | pubmed:pagination | 241-4 | lld:pubmed |
| pubmed-article:19601999 | pubmed:meshHeading | pubmed-meshheading:19601999... | lld:pubmed |
| pubmed-article:19601999 | pubmed:meshHeading | pubmed-meshheading:19601999... | lld:pubmed |
| pubmed-article:19601999 | pubmed:meshHeading | pubmed-meshheading:19601999... | lld:pubmed |
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| pubmed-article:19601999 | pubmed:meshHeading | pubmed-meshheading:19601999... | lld:pubmed |
| pubmed-article:19601999 | pubmed:meshHeading | pubmed-meshheading:19601999... | lld:pubmed |
| pubmed-article:19601999 | pubmed:meshHeading | pubmed-meshheading:19601999... | lld:pubmed |
| pubmed-article:19601999 | pubmed:meshHeading | pubmed-meshheading:19601999... | lld:pubmed |
| pubmed-article:19601999 | pubmed:meshHeading | pubmed-meshheading:19601999... | lld:pubmed |
| pubmed-article:19601999 | pubmed:meshHeading | pubmed-meshheading:19601999... | lld:pubmed |
| pubmed-article:19601999 | pubmed:meshHeading | pubmed-meshheading:19601999... | lld:pubmed |
| pubmed-article:19601999 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:19601999 | pubmed:articleTitle | A genetic polymorphism in transforming growth factor beta receptor-2 is associated with serum osteopontin. | lld:pubmed |
| pubmed-article:19601999 | pubmed:affiliation | Vascular Biology Unit, School of Medicine, James Cook University, Townsville, Queensland 4811, Australia. | lld:pubmed |
| pubmed-article:19601999 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19601999 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:19601999 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
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