| pubmed-article:19590001 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19590001 | lifeskim:mentions | umls-concept:C0024400 | lld:lifeskim |
| pubmed-article:19590001 | lifeskim:mentions | umls-concept:C0026565 | lld:lifeskim |
| pubmed-article:19590001 | lifeskim:mentions | umls-concept:C0277793 | lld:lifeskim |
| pubmed-article:19590001 | lifeskim:mentions | umls-concept:C1135809 | lld:lifeskim |
| pubmed-article:19590001 | lifeskim:mentions | umls-concept:C0205421 | lld:lifeskim |
| pubmed-article:19590001 | pubmed:issue | 5937 | lld:pubmed |
| pubmed-article:19590001 | pubmed:dateCreated | 2009-7-10 | lld:pubmed |
| pubmed-article:19590001 | pubmed:abstractText | Caloric restriction (CR), without malnutrition, delays aging and extends life span in diverse species; however, its effect on resistance to illness and mortality in primates has not been clearly established. We report findings of a 20-year longitudinal adult-onset CR study in rhesus monkeys aimed at filling this critical gap in aging research. In a population of rhesus macaques maintained at the Wisconsin National Primate Research Center, moderate CR lowered the incidence of aging-related deaths. At the time point reported, 50% of control fed animals survived as compared with 80% of the CR animals. Furthermore, CR delayed the onset of age-associated pathologies. Specifically, CR reduced the incidence of diabetes, cancer, cardiovascular disease, and brain atrophy. These data demonstrate that CR slows aging in a primate species. | lld:pubmed |
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| pubmed-article:19590001 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19590001 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19590001 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:19590001 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19590001 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:19590001 | pubmed:issn | 1095-9203 | lld:pubmed |
| pubmed-article:19590001 | pubmed:author | pubmed-author:WeindruchRich... | lld:pubmed |
| pubmed-article:19590001 | pubmed:author | pubmed-author:AllisonDavid... | lld:pubmed |
| pubmed-article:19590001 | pubmed:author | pubmed-author:BeasleyT... | lld:pubmed |
| pubmed-article:19590001 | pubmed:author | pubmed-author:AndersonRozal... | lld:pubmed |
| pubmed-article:19590001 | pubmed:author | pubmed-author:KemnitzJoseph... | lld:pubmed |
| pubmed-article:19590001 | pubmed:author | pubmed-author:JohnsonSterli... | lld:pubmed |
| pubmed-article:19590001 | pubmed:author | pubmed-author:ColmanRicki... | lld:pubmed |
| pubmed-article:19590001 | pubmed:author | pubmed-author:SimmonsHeathe... | lld:pubmed |
| pubmed-article:19590001 | pubmed:author | pubmed-author:KosmatkaKrist... | lld:pubmed |
| pubmed-article:19590001 | pubmed:author | pubmed-author:KastmanErik... | lld:pubmed |
| pubmed-article:19590001 | pubmed:author | pubmed-author:CruzenChristi... | lld:pubmed |
| pubmed-article:19590001 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19590001 | pubmed:day | 10 | lld:pubmed |
| pubmed-article:19590001 | pubmed:volume | 325 | lld:pubmed |
| pubmed-article:19590001 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19590001 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19590001 | pubmed:pagination | 201-4 | lld:pubmed |
| pubmed-article:19590001 | pubmed:dateRevised | 2010-9-24 | lld:pubmed |
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| pubmed-article:19590001 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:19590001 | pubmed:articleTitle | Caloric restriction delays disease onset and mortality in rhesus monkeys. | lld:pubmed |
| pubmed-article:19590001 | pubmed:affiliation | Wisconsin National Primate Research Center, University of Wisconsin, Madison, WI 53715, USA. rcolman@primate.wisc.edu | lld:pubmed |
| pubmed-article:19590001 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19590001 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:19590001 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
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