Botulinum toxin type A injection in alleviating postoperative pain and improving quality of life in lower extremity limb lengthening and deformity correction: a pilot study.

Source:http://linkedlifedata.com/resource/pubmed/id/19568011

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General Info

Authors

Hamdy RC, Platt RW, Aiona MD, Finley GA, Montpetit K, Thomas SS, McCarthy J, Raney EM, Chafetz RS, Fillman RR, Ruck-Gibis J, Littleton AG, MacKenzie W, Tamayo CM, Takahashi SN, Rinaldi M, Dahan-Oliel N

Affiliation

Shriners Hospital for Children, Montreal, Quebec, Canada. rhamdy@shriners.mcgill.ca

Abstract

The Ilizarov technique is commonly used for lengthening and deformity corrections of the lower limbs in children. Postoperative pain can be significant, affecting quality of life and functional mobility, and often requiring prolonged medication use. Several studies have investigated the antinociceptive actions of botulinum toxin type A (BtX-A), yet evidence for its use in this population is limited. The objectives were to (1) establish the feasibility of a randomized clinical trial in children undergoing limb lengthening or deformity correction and (2) provide preliminary evidence of the beneficial effects of BtX-A in this population.

PMID
19568011

Publication types

Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Multicenter Study