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pubmed-article:19506963pubmed:abstractTextPatients with synchronous colorectal liver metastases (CLM) are typically treated with initial colorectal resection followed by arbitrary and prolonged courses of chemotherapy. Partial hepatectomy is considered only for patients without interval disease progression. This review describes the rationale for this treatment approach and the recent developments suggesting that this management paradigm should be reconsidered.lld:pubmed
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pubmed-article:19506963pubmed:articleTitleSynchronous colorectal liver metastases: is it time to reconsider traditional paradigms of management?lld:pubmed
pubmed-article:19506963pubmed:affiliationDepartment of Surgery, Duke University Medical Center, Durham, NC, USA. reddy005@mc.duke.edulld:pubmed
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