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pubmed-article:19467028pubmed:dateCreated2009-10-23lld:pubmed
pubmed-article:19467028pubmed:abstractTextCopper plays a key role in several processes of skin formation and regeneration. Copper has been shown to be absorbed through intact skin. We hypothesized that sleeping on fabrics containing copper-impregnated fibres would have a positive cosmetic effect on the skin. The aim of this study was to confirm our hypothesis. A 4-week, double blind, parallel, randomized study was carried out in which 57 volunteers aged 40-60 years used either copper oxide containing pillowcases (0.4% weight/weight) or control pillowcases not containing copper. Photographs were taken by a professional photographer of each participant at the beginning of the study and at 2 and 4 weeks after the commencement of the study. Two expert graders (a dermatologist and a cosmetologist) evaluated the pictures for the effect on several cosmetic facial skin characteristics. The copper-containing pillowcases had a positive effect for the following facial characteristics: reduction of wrinkles (P < 0.001) and crow's feet/fine lines (P < 0.001) and improvement of general appearance (P < 0.001) at both 2 and 4 weeks. The differences were statistically significant (Wilcoxon scores and chi-squared tests). Consistent sleeping for 4 weeks on copper oxide containing pillowcases caused a significant reduction in the appearance of facial wrinkles and crow's feet/fine lines and significant improvement in the appearance of facial skin. In most trial participants, this effect was already noticeable within 2 weeks of using the copper oxide containing pillowcases.lld:pubmed
pubmed-article:19467028pubmed:languageenglld:pubmed
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pubmed-article:19467028pubmed:authorpubmed-author:HuszarMMlld:pubmed
pubmed-article:19467028pubmed:authorpubmed-author:GabbayJJlld:pubmed
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pubmed-article:19467028pubmed:authorpubmed-author:LyakhovitskyA...lld:pubmed
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pubmed-article:19467028pubmed:volume31lld:pubmed
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pubmed-article:19467028pubmed:pagination437-43lld:pubmed
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pubmed-article:19467028pubmed:year2009lld:pubmed
pubmed-article:19467028pubmed:articleTitleImprovement of facial skin characteristics using copper oxide containing pillowcases: a double-blind, placebo-controlled, parallel, randomized study.lld:pubmed
pubmed-article:19467028pubmed:affiliationCupron Inc., North Industrial Area, Beth Shemesh, Israel. gadi@cupron.comlld:pubmed
pubmed-article:19467028pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:19467028pubmed:publicationTypeRandomized Controlled Triallld:pubmed
pubmed-article:19467028pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed