| pubmed-article:19449665 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19449665 | lifeskim:mentions | umls-concept:C0007452 | lld:lifeskim |
| pubmed-article:19449665 | lifeskim:mentions | umls-concept:C0000890 | lld:lifeskim |
| pubmed-article:19449665 | lifeskim:mentions | umls-concept:C0598741 | lld:lifeskim |
| pubmed-article:19449665 | lifeskim:mentions | umls-concept:C0248572 | lld:lifeskim |
| pubmed-article:19449665 | lifeskim:mentions | umls-concept:C0529813 | lld:lifeskim |
| pubmed-article:19449665 | lifeskim:mentions | umls-concept:C0323498 | lld:lifeskim |
| pubmed-article:19449665 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:19449665 | pubmed:dateCreated | 2009-5-19 | lld:pubmed |
| pubmed-article:19449665 | pubmed:abstractText | Steers were treated with doramectin or eprinomectin by daily oral capsule for 28 consecutive days. The level of doramectin in the serum of steers treated at 200 microg/kg/d reached a maximum of 104.0 +/- 22.1 ppb at day 21 and declined from 93.3 +/- 20.5 ppb on the final day of treatment to below detectable by day 56. Steers treated at 50 microg/kg/d reached a maximum level of doramectin in the serum of 24.7 +/- 1.2 ppb on day 21 and declined from 24.7 +/- 0.6 ppb on the final day of treatment to less than detectable on day 42. Both doramectin dosages provided 100% control of estimated larvae (EL) of Amblyomma americanum (L.) (Acari: Ixodidae) throughout the 28-d treatment period. Daily oral treatment with eprinomectin at a dosage of 200 microg/kg for 28 consecutive days produced a maximum concentration in the serum of 41.6 +/- 11.0 ppb at day 14. On the final day of eprinomectin treatment, the serum concentration was 38.3 +/- 5.9 ppb. Seven days later at day 35, eprinomectin was not detectable in the serum. For steers treated at 50 microg/kg/d for 28 consecutive days, the serum level of eprinomectin reached a maximum of 10.0 +/- 3.0 ppb on day 28 and was undetectable on day 35. Both eprinomectin dosages provided complete control of EL of A. americanum during the 28-d treatment period. Because eprinomectin is efficacious against A. americanum at lower serum levels in cattle and is eliminated from the serum at a more rapid rate than either doramectin or ivermectin, it provides advantages for use in applications such as the medicated bait for control of ticks on white-tailed deer and could have potential for use in the Cattle Fever Tick Eradication Program. | lld:pubmed |
| pubmed-article:19449665 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19449665 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19449665 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19449665 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19449665 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19449665 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19449665 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19449665 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19449665 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:19449665 | pubmed:issn | 0022-0493 | lld:pubmed |
| pubmed-article:19449665 | pubmed:author | pubmed-author:MillerJ AJA | lld:pubmed |
| pubmed-article:19449665 | pubmed:author | pubmed-author:OehlerD DDD | lld:pubmed |
| pubmed-article:19449665 | pubmed:author | pubmed-author:PoundJ MJM | lld:pubmed |
| pubmed-article:19449665 | pubmed:author | pubmed-author:LohmeyerK HKH | lld:pubmed |
| pubmed-article:19449665 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:19449665 | pubmed:volume | 102 | lld:pubmed |
| pubmed-article:19449665 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19449665 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19449665 | pubmed:pagination | 809-14 | lld:pubmed |
| pubmed-article:19449665 | pubmed:meshHeading | pubmed-meshheading:19449665... | lld:pubmed |
| pubmed-article:19449665 | pubmed:meshHeading | pubmed-meshheading:19449665... | lld:pubmed |
| pubmed-article:19449665 | pubmed:meshHeading | pubmed-meshheading:19449665... | lld:pubmed |
| pubmed-article:19449665 | pubmed:meshHeading | pubmed-meshheading:19449665... | lld:pubmed |
| pubmed-article:19449665 | pubmed:meshHeading | pubmed-meshheading:19449665... | lld:pubmed |
| pubmed-article:19449665 | pubmed:meshHeading | pubmed-meshheading:19449665... | lld:pubmed |
| pubmed-article:19449665 | pubmed:meshHeading | pubmed-meshheading:19449665... | lld:pubmed |
| pubmed-article:19449665 | pubmed:meshHeading | pubmed-meshheading:19449665... | lld:pubmed |
| pubmed-article:19449665 | pubmed:meshHeading | pubmed-meshheading:19449665... | lld:pubmed |
| pubmed-article:19449665 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:19449665 | pubmed:articleTitle | Efficacy of eprinomectin and doramectin against Amblyomma americanum (Acari: Ixodidae) on cattle. | lld:pubmed |
| pubmed-article:19449665 | pubmed:affiliation | USDA-ARS, Knipling-Bushland U.S. Livestock Insects Research Laboratory, 2700 Fredericksburg Road, Kerrville, TX 78028, USA. kim.lohmeyer@ars.usda.gov | lld:pubmed |
| pubmed-article:19449665 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19449665 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
