Nilotinib (AMN107, Tasigna) reverses multidrug resistance by inhibiting the activity of the ABCB1/Pgp and ABCG2/BCRP/MXR transporters.

Source:http://linkedlifedata.com/resource/pubmed/id/19427995

Biochem. Pharmacol. 2009 Jul 15 78 2 153-61

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19427995