pubmed-article:19423954 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:19423954 | lifeskim:mentions | umls-concept:C0999699 | lld:lifeskim |
pubmed-article:19423954 | lifeskim:mentions | umls-concept:C0027061 | lld:lifeskim |
pubmed-article:19423954 | lifeskim:mentions | umls-concept:C0034090 | lld:lifeskim |
pubmed-article:19423954 | lifeskim:mentions | umls-concept:C1621574 | lld:lifeskim |
pubmed-article:19423954 | lifeskim:mentions | umls-concept:C1314939 | lld:lifeskim |
pubmed-article:19423954 | lifeskim:mentions | umls-concept:C0971705 | lld:lifeskim |
pubmed-article:19423954 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:19423954 | pubmed:dateCreated | 2009-5-15 | lld:pubmed |
pubmed-article:19423954 | pubmed:abstractText | We examined the involvement of the Na(+)/Ca(2+) exchanger in the automaticity of the pulmonary vein myocardium with a specific inhibitor, SEA0400. Action potentials were recorded from the myocardial layer of isolated guinea-pig pulmonary vein preparations, and Ca(2+) transients were recorded from the cardiomyocytes. Spontaneous electrical activity was observed in 17.7% of the preparations, which was inhibited by either SEA0400 or ryanodine. In quiescent preparations, ouabain induced electrical activity and spontaneous Ca(2+) transients, which were inhibited by SEA0400, as well as ryanodine. These results provide pharmacological evidence that the Na(+)/Ca(2+) exchanger underlies the automaticity of the pulmonary vein myocardium. | lld:pubmed |
pubmed-article:19423954 | pubmed:language | eng | lld:pubmed |
pubmed-article:19423954 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:19423954 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:19423954 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:19423954 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:19423954 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:19423954 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:19423954 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:19423954 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:19423954 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:19423954 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:19423954 | pubmed:month | May | lld:pubmed |
pubmed-article:19423954 | pubmed:issn | 1347-8613 | lld:pubmed |
pubmed-article:19423954 | pubmed:author | pubmed-author:TakedaKiyoshi... | lld:pubmed |
pubmed-article:19423954 | pubmed:author | pubmed-author:TanakaHikaruH | lld:pubmed |
pubmed-article:19423954 | pubmed:author | pubmed-author:ShigenobuKoki... | lld:pubmed |
pubmed-article:19423954 | pubmed:author | pubmed-author:HideakiShimad... | lld:pubmed |
pubmed-article:19423954 | pubmed:author | pubmed-author:TakaharaAkira... | lld:pubmed |
pubmed-article:19423954 | pubmed:author | pubmed-author:KawanishiToru... | lld:pubmed |
pubmed-article:19423954 | pubmed:author | pubmed-author:NamekataIyuki... | lld:pubmed |
pubmed-article:19423954 | pubmed:author | pubmed-author:TsuneokaYayoi... | lld:pubmed |
pubmed-article:19423954 | pubmed:author | pubmed-author:SugimotoTakah... | lld:pubmed |
pubmed-article:19423954 | pubmed:author | pubmed-author:NagaharuMidor... | lld:pubmed |
pubmed-article:19423954 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:19423954 | pubmed:volume | 110 | lld:pubmed |
pubmed-article:19423954 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:19423954 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:19423954 | pubmed:pagination | 111-6 | lld:pubmed |
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pubmed-article:19423954 | pubmed:year | 2009 | lld:pubmed |
pubmed-article:19423954 | pubmed:articleTitle | Involvement of the Na(+)/Ca(2+) exchanger in the automaticity of guinea-pig pulmonary vein myocardium as revealed by SEA0400. | lld:pubmed |
pubmed-article:19423954 | pubmed:affiliation | Department of Pharmacology, Toho University Faculty of Pharmaceutical Sciences, Japan. iyuki@phar.toho-u.ac.jp | lld:pubmed |
pubmed-article:19423954 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:19423954 | pubmed:publicationType | In Vitro | lld:pubmed |
pubmed-article:19423954 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |