| pubmed-article:19414554 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19414554 | lifeskim:mentions | umls-concept:C1655731 | lld:lifeskim |
| pubmed-article:19414554 | lifeskim:mentions | umls-concept:C0021920 | lld:lifeskim |
| pubmed-article:19414554 | lifeskim:mentions | umls-concept:C1442161 | lld:lifeskim |
| pubmed-article:19414554 | lifeskim:mentions | umls-concept:C0017351 | lld:lifeskim |
| pubmed-article:19414554 | lifeskim:mentions | umls-concept:C0086222 | lld:lifeskim |
| pubmed-article:19414554 | lifeskim:mentions | umls-concept:C0699032 | lld:lifeskim |
| pubmed-article:19414554 | lifeskim:mentions | umls-concept:C1879547 | lld:lifeskim |
| pubmed-article:19414554 | lifeskim:mentions | umls-concept:C1705733 | lld:lifeskim |
| pubmed-article:19414554 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:19414554 | pubmed:dateCreated | 2009-5-12 | lld:pubmed |
| pubmed-article:19414554 | pubmed:abstractText | A tissue-specific transcriptional enhancer, Emu, has been implicated in developmentally regulated recombination and transcription of the immunoglobulin heavy chain (IgH) gene locus. We demonstrate that deleting 220 nucleotides that constitute the core Emu results in partially active locus, characterized by reduced histone acetylation, chromatin remodeling, transcription, and recombination, whereas other hallmarks of tissue-specific locus activation, such as loss of H3K9 dimethylation or gain of H3K4 dimethylation, are less affected. These observations define Emu-independent and Emu-dependent phases of locus activation that reveal an unappreciated epigenetic hierarchy in tissue-specific gene expression. | lld:pubmed |
| pubmed-article:19414554 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19414554 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19414554 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19414554 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19414554 | pubmed:month | May | lld:pubmed |
| pubmed-article:19414554 | pubmed:issn | 1540-9538 | lld:pubmed |
| pubmed-article:19414554 | pubmed:author | pubmed-author:ZhangYuY | lld:pubmed |
| pubmed-article:19414554 | pubmed:author | pubmed-author:AltFrederick... | lld:pubmed |
| pubmed-article:19414554 | pubmed:author | pubmed-author:ChakrabortyTi... | lld:pubmed |
| pubmed-article:19414554 | pubmed:author | pubmed-author:SenRanjanR | lld:pubmed |
| pubmed-article:19414554 | pubmed:author | pubmed-author:IvanovaIrinaI | lld:pubmed |
| pubmed-article:19414554 | pubmed:author | pubmed-author:PerlotThomasT | lld:pubmed |
| pubmed-article:19414554 | pubmed:author | pubmed-author:SubrahmanyamR... | lld:pubmed |
| pubmed-article:19414554 | pubmed:author | pubmed-author:JaniAnantA | lld:pubmed |
| pubmed-article:19414554 | pubmed:author | pubmed-author:GoffPeter HPH | lld:pubmed |
| pubmed-article:19414554 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19414554 | pubmed:day | 11 | lld:pubmed |
| pubmed-article:19414554 | pubmed:volume | 206 | lld:pubmed |
| pubmed-article:19414554 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19414554 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19414554 | pubmed:pagination | 1019-27 | lld:pubmed |
| pubmed-article:19414554 | pubmed:dateRevised | 2010-12-3 | lld:pubmed |
| pubmed-article:19414554 | pubmed:meshHeading | pubmed-meshheading:19414554... | lld:pubmed |
| pubmed-article:19414554 | pubmed:meshHeading | pubmed-meshheading:19414554... | lld:pubmed |
| pubmed-article:19414554 | pubmed:meshHeading | pubmed-meshheading:19414554... | lld:pubmed |
| pubmed-article:19414554 | pubmed:meshHeading | pubmed-meshheading:19414554... | lld:pubmed |
| pubmed-article:19414554 | pubmed:meshHeading | pubmed-meshheading:19414554... | lld:pubmed |
| pubmed-article:19414554 | pubmed:meshHeading | pubmed-meshheading:19414554... | lld:pubmed |
| pubmed-article:19414554 | pubmed:meshHeading | pubmed-meshheading:19414554... | lld:pubmed |
| pubmed-article:19414554 | pubmed:meshHeading | pubmed-meshheading:19414554... | lld:pubmed |
| pubmed-article:19414554 | pubmed:meshHeading | pubmed-meshheading:19414554... | lld:pubmed |
| pubmed-article:19414554 | pubmed:meshHeading | pubmed-meshheading:19414554... | lld:pubmed |
| pubmed-article:19414554 | pubmed:meshHeading | pubmed-meshheading:19414554... | lld:pubmed |
| pubmed-article:19414554 | pubmed:meshHeading | pubmed-meshheading:19414554... | lld:pubmed |
| pubmed-article:19414554 | pubmed:meshHeading | pubmed-meshheading:19414554... | lld:pubmed |
| pubmed-article:19414554 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:19414554 | pubmed:articleTitle | A 220-nucleotide deletion of the intronic enhancer reveals an epigenetic hierarchy in immunoglobulin heavy chain locus activation. | lld:pubmed |
| pubmed-article:19414554 | pubmed:affiliation | Laboratory of Cellular and Molecular Biology, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA. | lld:pubmed |
| pubmed-article:19414554 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19414554 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:19414554 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| pubmed-article:19414554 | pubmed:publicationType | Research Support, N.I.H., Intramural | lld:pubmed |
| entrez-gene:19374 | entrezgene:pubmed | pubmed-article:19414554 | lld:entrezgene |
| entrez-gene:111507 | entrezgene:pubmed | pubmed-article:19414554 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:19414554 | lld:pubmed |
